Two key metrics of signal detection theory, perceptual certainty and response bias, correlate with changes in cognitive fatigue.
Changes in functional connectivity within the fatigue network occur in response to cognitive fatigue.
People with spinal cord injuries have the same brain activity during processing speed tasks as healthy older adults. The findings suggest the theory of accelerated cognitive aging following SCI is correct.
Those with MS allocate neural resources less effectively when faced with increased cognitive task demands, and this likely results in the increased mental fatigue those with the neurodegenerative disorder experience.
Using a modified story memory technique, people with multiple sclerosis showed improvements in learning and memory. Additionally, fMRI neuroimaging revealed changes in brain activity related to working memory and word encoding.
Researchers report hippocampal plasticity can be improved by aerobic exercise and memory retraining for those with MS.