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Kcc2

·December 9, 2025·7 min read

Key Brain Protein Controls How We Learn Reward Cues

Changing levels of the brain protein KCC2 can alter how reward associations form, reshaping the learning process that links cues to outcomes. Reduced KCC2 activity increased dopamine neuron firing and strengthened new cue–reward connections, offering insight into how addictions and maladaptive habits develop.

This shows a child looking at a DNA double helix

Autism Featured Genetics Neuroscience

·May 24, 2019·4 min read

New approaches to study the genetics of autism may lead to new therapies

Researchers will present their latest findings regarding genes associated with autism spectrum disorder in an upcoming meeting.

Featured Neurology

·July 19, 2018·5 min read

Paralyzed Mice with Spinal Cord Injury Made to Walk Again

Researchers have successfully restored the ability to walk in mice paralyzed as a result of spinal cord injuries with the help of a small molecular compound.

Featured Genetics Neuroscience Psychology

·December 27, 2017·7 min read

Shedding Light on Cause of Postpartum Depression

Researchers report a protein that mediates dysregulation of the HPA axis may induce postpartum disorder in some new moms.

Featured Neuroscience Psychology

·November 6, 2016·4 min read

Stressed Out Rats Consume More Alcohol

A new study explains the effects of stress on increased alcohol consumption due to changes in the brain's reward center.

Image shows Kcc2 in a mouse's olfactory bulb.

Featured Neuroscience

·July 8, 2016·4 min read

Time Switch in the Brain Improves Sense of Smell

Researchers investigate how similar scents are differentiated.

Image shows human cells from a patient with Rett syndrome.

Autism Featured

·January 4, 2016·2 min read

New Drug Target May Lead to Novel Treatment for Severe Autism

Findings could lead to new treatments for Rett Syndrome and other forms of autism, researchers report.

Image shows a number of microscopic images of impaired cell surface expression of KCC2.

Featured Genetics Neurology Open Neuroscience Articles

·September 3, 2015·3 min read

Mutation in Genetic Encoding Behind Infant Epilepsy

Researchers discover a new mechanism that appears to be responsible for infant epilepsy.

This image shows scans of brains expressing different levels of Bmal1.

Featured Neuroscience

·June 29, 2015·3 min read

It’s Summer and Your Brain Knows It

Researchers have discovered an important mechanism which allows animals to effectively track seasonal changes.

This image shows a human head with electrical signals imprinted into the middle of it.

Featured Genetics Neurology Open Neuroscience Articles

·June 16, 2014·4 min read

Study Yields Important Clues to the Genetics of Epilepsy

Researchers have discovered a significant genetic component of IGE.

This image shows the outline of a head against a blue background.

Featured Neurology

·June 6, 2014·4 min read

Researchers Pave the Way for Improved Epilepsy Treatments

New findings could pave the way for developing improved epilepsy treatments and therapies for other neurological disorders.

The image shows the chemical structure of bisphenol A.

Featured Neurology Open Neuroscience Articles

·February 25, 2013·3 min read

BPA May Affect the Developing Brain by Disrupting Gene Regulation

New research suggests environmental exposure to bisphenol A (BPA), a chemical commonly found in plastics and resins, could suppress a gene critical to nerve cell function and the development of the central nervous system. Exposure to BPA could predispose humans to a number of neurodevelopmental and other health disorders.