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inhibitory neurons

Illustration of chandelier cells connecting to pyramidal neurons in the brain.

Featured Genetics Neurology Neuroscience

·January 13, 2026·3 min read

Brain Conductors Find Precise Connection to Target Cells via Protein Handshake

Researchers identify two key proteins that allow chandelier cells to connect with excitatory neurons. This "handshake" regulates brain signals and, when disrupted, may lead to epilepsy or autism.

Neuroscience

·December 14, 2025·7 min read

Balanced Brain Inhibition Found Essential for Recognition Memory

A new study shows that balanced neural inhibition in the hippocampus is crucial for recognition memory, the ability to remember objects we’ve recently encountered. Using a rat model, researchers altered GABA-mediated inhibition in either the hippocampus or prefrontal cortex to see how each region contributed to memory.

This shows hippocampal neurons, and is an AI representation.

Featured Neuroscience

·August 18, 2025·5 min read

New Neuron Type Controls How Accurately We Recall Memories

Scientists have identified a previously unknown group of inhibitory neurons defined by the adhesion molecule Kirrel3. These neurons receive input from dentate granule cells and project strongly onto CA3 hippocampal neurons, placing them at a critical juncture for memory retrieval.

Featured Genetics Neuroscience

·July 8, 2025·5 min read

Later-Born Neurons Mature Faster to Keep Networks in Balance

The brain depends on a delicate balance between excitatory and inhibitory neurons to function properly. A new study reveals that inhibitory neurons born later in development mature more quickly than earlier ones, allowing them to catch up and integrate evenly into neural networks.

This shows AI representations of neurons.

Featured Neuroscience

·June 2, 2025·6 min read

Inhibitory Neurons May Hold the Key to Spatial Learning and Memory

A new study explores how the brain quickly learns and remembers important locations by focusing not on excitatory neurons, but on inhibitory ones called parvalbumin interneurons (PVs). These PVs act like circuit breakers, briefly reducing their activity to allow learning-related neurons to strengthen connections. Using optogenetics and virtual reality mazes in mice, researchers found that learning was blocked when PV inhibition didn’t decrease at the right time.

Featured Neuroscience

·November 18, 2019·5 min read

The difference between an expert’s brain and a novice’s

When learning a new task, brain activities alter over time as mice transition to an expert from a novice. The changes are reflected in neural networks and neural activity. As the animal's knowledge grows, neural networks become more focused.

Featured Neuroscience

·August 27, 2018·6 min read

New Kind of Human Brain Cell Identified

Researchers have identified a new type of human neuron which they have dubbed the 'rosehip neuron'. The newly discovered cells are inhibitory neurons which may only be found in human and primate brains.

Electrophysiology Featured Neuroscience Open Neuroscience Articles

·April 18, 2018·4 min read

Keeping the Excitement Under Control

Researchers have developed a new method to identify and monitor the activity of 'quiet' neurons.

Featured Neurology

·June 27, 2017·2 min read

Seizures Follow Similar Path Regardless of Speed

By capturing a cell by cell view of seizures propagating through a mouse brain, researchers discovered neurons fire in a sequential pattern, regardless of how quickly the seizure occurs. The findings confirm seizures are not a result of neurons going haywire.