Deletion of the neurodegenerative disease associated microglial gene CX3CR1 aggravated the disease state and increased the accumulation of plaques in the brains of mouse models of Alzheimer's disease. Deficiencies of the gene also impaired the movement of microglia toward the plaques.
Researchers have identified an autophagy pathway in hair cells in the ear that's linked to permanent hearing loss that occurs as a result of exposure to aminoglycosides antibiotics in some patients.
Targeting synaptic calcium permeable receptors in the nucleus accumbens and blocking them could delay or prevent the onset of Alzheimer's associated neuropsychiatric symptoms, and ultimately cognitive decline.
Niaspan, an FDA-approved drug, limits disease progression in lab models of Alzheimer's disease.
While the stigma against depression has decreased for the first time, the stigma levels for other mental health disorders have either remained stagnant or increased.
A new brain model explored bursts of human brain activity never before studied. The bursts may serve as potential biomarkers for depression, dementia, schizophrenia, and ADHD.
Deleting ABI3, a gene associated with Alzheimer's disease, significantly increased amyloid-beta accumulation in the brain and decreased the amount of microglia around amyloid-plaques, researchers report.
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Those who live in neighborhoods that are considered safe, orderly, and have a more interconnected social environment are at higher risk of embarking on binge drinking episodes, a new study reports.