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imba

·September 26, 2024·4 min read

Scientists Discover Potential to Pause Human Embryo Development

Researchers have identified a molecular mechanism in human cells that mimics embryonic diapause, a process some mammals use to pause development. By inhibiting the mTOR signaling pathway in stem cell-derived blastoids, scientists induced a dormant state similar to that found in other mammals.

Featured Neurology Neuroscience

·December 5, 2023·5 min read

Dopaminergic System Organoid Model Illuminates Parkinson’s and Addiction

Researchers developed a novel organoid model that mimics the human dopaminergic system, providing crucial insights into Parkinson's disease and the impact of chronic cocaine use. This study demonstrates the model's ability to replicate the structure, connectivity, and functionality of the dopaminergic system.

Autism Featured Genetics Neuroscience

·September 13, 2023·6 min read

Innovative Gene Screening in Human Tissue May Unlock Autism’s Secrets

Researchers pioneered a groundbreaking method called "CHOOSE" to investigate genes tied to autism spectrum disorder (ASD) within human tissue. This technique allows for simultaneous examination of key transcriptional regulator genes linked to autism in a single organoid. Utilizing CHOOSE, the team pinpointed mutations in 36 genes known to heighten autism risk, shedding light on how they influence brain development.