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IL-10

·November 16, 2020·4 min read

Chronic Alcohol Use Reshapes the Brain’s Immune Landscape, Driving Anxiety and Addiction

Study identifies inflammatory mechanisms and cellular activity in the amygdala that drives alcohol addiction in mice. Chronic alcohol exposure compromises immune cells in the brain, driving anxiety and alcohol consumption that may lead to the development of AUD.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·October 16, 2019·4 min read

Frontotemporal dementia is associated with alterations in immune system function

Researchers discovered increased inflammatory activity in a subgroup of patients with frontotemporal dementia. The increased inflammation was indicated by elevated levels of cytokines known to increase inflammatory response and decreased levels of IL-10, which reduces inflammation. The inflammation was associated with Parkinsonism's symptoms and rapid cognitive and functional decline. The study also revealed patients with FTD are less likely to develop cancer.

This shows the outline of a head and brain

Featured Neurology Neuroscience Open Neuroscience Articles

·May 14, 2019·4 min read

Probiotic-derived molecule may suppress fatal brain inflammation

Capsular polysaccharide A (PSA), an envelope molecule, may help to boost the immune system and protect against potentially fatal neuroinflammation associated with Herpes Simplex Encephalitis (HSE). Mice given PSA survived exposure to a lethal herpes simplex viral infection, while those not treated with the probiotic did not, despite both groups being treated with a common antiviral used to treat HSE.

Featured Neurology Neuroscience Open Neuroscience Articles

·December 18, 2018·6 min read

Immune Response May Trigger Chronic Fatigue Syndrome

Researchers report an exaggerated immune response can trigger chronic fatigue syndrome. The study reveals levels of Il-10 were higher in those who developed lasting fatigue, suggesting the immune system may have been primed to over respond.

Featured Genetics Neuroscience

·May 9, 2017·2 min read

Key Pathway in Inflammation and Aging Identified

Findings provide insight into key processes of inflammation and could also have implications for treating neurodegenerative diseases, researchers report.