Study identifies inflammatory mechanisms and cellular activity in the amygdala that drives alcohol addiction in mice. Chronic alcohol exposure compromises immune cells in the brain, driving anxiety and alcohol consumption that may lead to the development of AUD.
Researchers discovered increased inflammatory activity in a subgroup of patients with frontotemporal dementia. The increased inflammation was indicated by elevated levels of cytokines known to increase inflammatory response and decreased levels of IL-10, which reduces inflammation. The inflammation was associated with Parkinsonism's symptoms and rapid cognitive and functional decline. The study also revealed patients with FTD are less likely to develop cancer.
Capsular polysaccharide A (PSA), an envelope molecule, may help to boost the immune system and protect against potentially fatal neuroinflammation associated with Herpes Simplex Encephalitis (HSE). Mice given PSA survived exposure to a lethal herpes simplex viral infection, while those not treated with the probiotic did not, despite both groups being treated with a common antiviral used to treat HSE.
Researchers report an exaggerated immune response can trigger chronic fatigue syndrome. The study reveals levels of Il-10 were higher in those who developed lasting fatigue, suggesting the immune system may have been primed to over respond.