Opiate exposure causes synaptic rewiring in the nucleus accumbens in addition to decreasing dendritic spines. The findings shed light into the neurobiology of opiate relapse.
A new study reports researchers have successfully reversed memory loss in fly models of Alzheimer's disease by restoring the balance between to enzymes that regulate gene expression.
Researchers discover targeting the HDAC2 enzyme, by blocking its interaction with Sp3, resulted in the reversal of memory loss in mice. The findings, published in Cell Reports, may offer a new avenue for treating memory loss in Alzheimer's disease.
A new study reports a protein associated with Rett syndrome is also among a group of three proteins that affect the function of a gene previously linked to OCD.
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Neuroscientists show that HDAC2 enzyme could be a good target for new drugs. MIT neuroscientists have shown that an enzyme...