Researchers have identified high levels of three gut-produced toxic metabolites in plasma and cerebrospinal fluid samples of patients with multiple sclerosis.
A new review of almost 200 publications suggests the gut microbiota may play a critical role in modulating brain function, social behavior and other symptoms of autism.
Microglia, a key immune cell in the brain, appears to mediate the relationship between the gut microbiome and amyloid-beta deposits in male mouse models of Alzheimer's disease.
A species of gut bacteria called Lactobacillus apis has been linked to enhanced memory and cognition in bumblebees.
For people with arthritis, exercise reduces pain and lowers levels of inflammatory cytokines. Exercise also increases the production of natural endocannabinoids. Researchers found the way exercise promotes these changes was due to altered gut microbes.
The vascular barrier in the choroid plexus locks down access to the brain in response to gut inflammation that causes IBD. The dysregulated activity of the gut-brain vascular axis appears to protect the brain from inflammation. However, the mechanism may increase the risk of both cognitive and mental health problems associated with IBD.
Glial cells coordinate immune responses in the gut following infection. Researchers report glial cells could be targets for therapeutics to treat inflammatory bowel disorders.
Fenchol, a natural compound found in basil and other plans, appears to have a neuroprotective effect against Alzheimer's disease. Fenchol reduces the formation of zombie neural cells and increases the degradation of non-functional amyloid beta, allowing for quicker clearance of the protein from the brain.
Findings shed new light on the gut's enteric nervous system, offering hope for treatments for a range of disorders.
Researchers evaluate the role of the gut-brain axis in relation to health conditions and report on how gut-based interventions could provide relief for some mental health disorders.
An overgrowth in the gastrointestinal tract of the bacteria Klebsiella in preterm babies was associated with an increased presence of certain immune cells and the development of neurological damage. The findings suggest a link between microbiota and brain development.
Study highlights how the enteric nervous system acts similarly to neural networks in the brain and spinal cord.
