Specific combinations of microorganisms in the gut can worsen symptoms of multiple sclerosis in mouse models of the autoimmune disease. Read More
Study provides evidence of gut dysbiosis associated with Huntington's disease. Some of the gut measures were associated with disease symptoms such as movement and cognitive impairment. The findings could provide a new avenue of treatment for the neurodegenerative disease. Read More
Sensory neurons that send signals from the intestines to the brain stem extend to the interface of areas of the intestine that are exposed to high levels of microbial compounds. Turning off the neurons, researchers observed activated neurons in the brainstem as well as activation of gut neurons that control intestinal motility. The findings shed light on the potential mechanisms behind neurological abnormalities and intestinal diseases, including IBS. Read More
Specific genetic mutations affect both the existence and amount of particular bacteria in the gut. Read More
Building on previous research that links gut bacteria to the development of Parkinson's disease, researchers identified a probiotic which prevents the formation of alpha-synuclein. Read More
Microbiota-derived short-chain fatty acids (SCFA) modulate stroke recovery. The effect was mediated by circulating lymphocytes on microglia activation. The study reports SCFAs could be a potential therapeutic to improve post-stroke recovery. Read More
Study reflects on the possible use of fecal microbiome transplants and pre/probiotics to help with the treatment of Parkinson's disease. Findings reveal fecal transplants have not yet been proven to be effective for motor symptoms associated with the condition, and probiotics have only been shown to assist with constipation. Read More
Transplanting gut microbiota from older mice to younger germ-free mice increased hippocampal neurogenesis and intestinal growth. Read More
Researchers propose future gut microbiome studies related to Parkinson's disease should address questions relevant to patient care. Read More
Both human and mouse fetuses have their own microbiome, which is transmitted from the mother. Findings provide new avenues for interventions during pregnancy to stimulate the fetal microbiome when the mother shows risk of premature birth. Read More
The mode of delivery at birth is a significant factor in the composition of gut bacteria. Children born via cesarean section have reduced levels of 'good' bacteria and an increased number of pathogens linked to the hospital environment. Read More
Study adds to the growing body of evidence that the microbiome may impact muscle mass and physical function. In high-functioning older adults and mouse models, researchers identified higher levels of good bacteria in the microbiome than in their lower-functioning peers. Read More
