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glycogen

·July 1, 2025·5 min read

Clearing Brain Sugar Stores Could Protect Against Dementia

New research reveals that sugar metabolism in brain cells may be a crucial defense against Alzheimer’s and related dementias. Scientists found that neurons in both flies and human models of tauopathy accumulate excess glycogen, which disrupts cellular stress management when it can’t be broken down.

Featured Neuroscience

·May 26, 2021·6 min read

Fundamental Roles of Glucosamine in Brain Revealed

Glucosamine is a major component of brain glycogen, a new study reports.

This image is a brain slice showing glycogen accumulation in the brain.

Featured Neuroscience

·February 28, 2014·4 min read

Researchers Reveal the Dual Role of Brain Glycogen

Researchers report an accumulation of glycogen in Lafora disease directly causes apoptosis, triggers autophagy and synaptic failure.

Featured Neuroscience

·May 2, 2012·2 min read

Glycogen Accumulation in Neurons Causes Brain Damage and Shortens Lives of Flies and Mice

Work by IRB Barcelona researchers will further the study of neurodegenerative diseases such as Lafora progressive myoclonic epilepsy. Collaborative research...