Inducing gamma oscillations with visual stimulation via a process known as gamma entrainment using sensory stimuli, or GENUS, was shown to reduce amyloid plaques and phosphorylated tau in mouse models of dementia. Providing GENUS daily during the early stages of neurodegeneration helps preserve neural and synaptic density across multiple brain areas and improves cognitive performance for learning and spatial memory tasks.
Multisensory gamma wave stimulation improves recognition and spatial memory, in addition to reducing amyloid in the auditory cortex and hippocampal CA1 areas of mice. Findings suggest such sensory stimulation boosts hippocampal function and reduces Alzheimer's linked pathologies throughout the neocortex.