Metformin, a drug commonly used to treat diabetes, slows cognitive decline and reduces dementia risk in older people with diabetes.
Study reveals there is no link between memory decline and statin use in older adults. Additionally, no association was found between statin use and cognitive decline in those with genetic risk factors for dementia.
A combination of chronic stress and high-calorie diets raised insulin levels tenfold in the amygdala of mice. Prolonged high levels of insulin in the central amygdala resulted in neurons becoming desensitized to insulin. The desensitized neurons boosted NPY levels, which promoted eating and reduced the normal homeostasis response to burn calories. The findings may shed light on why some indulge in high-calorie foods when stressed, and why this may lead to obesity.