The autism-linked Gabrb3 gene appears to shape the formation of both normal and atypical neural connections in the brain.
Study found genes implicated in cattle temperament contribute to neural developmental functions and are differentially expressed in the human brain. Some ASD related genes are associated with cattle temperament.
Isoguavacine, an old experimental compound which exclusively targets peripheral neurons, mitigates abnormal touch sensitivity in mouse models of ASD. The compound also improved body mass, reduces anxiety, and in one genetic subset of mice, prevented the development of brain abnormalities that arise from altered touch response.
A new study reports some aspects of autism spectrum disorders are linked to defects in how peripheral nerves communicate sensory information to the brain.
