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FGF21

·April 25, 2026·7 min read

Liver Talks to the Brain to Control Appetite

A new study identifies a specific hindbrain circuit that regulates energy balance and food intake in response to dietary protein levels.

Featured Neuroscience

·March 7, 2023·4 min read

A Sobering Shot: Drunk Mice Sober Up After a Hormone Shot

Increasing concentrations of fibroblast growth factor 21 (FGF21) via injection dramatically accelerates recovery from intoxication in mice.

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Featured Neuroscience

·July 10, 2020·3 min read

Brain Cells that Trigger Sugar Cravings and Consumption Identified

FGF21, a hormone created in the liver in response to increased levels of sugar, acts in the brain to suppress sugar intake and controls the preference for sweet-tasting foods.

Featured Neuroscience Open Neuroscience Articles

·November 14, 2019·4 min read

Bacteria in the gut may alter aging process

Transplanting gut microbiota from older mice to younger germ-free mice increased hippocampal neurogenesis and intestinal growth.

Featured Genetics Neuroscience Open Neuroscience Articles

·October 29, 2018·4 min read

Obese Mice Lose a Third of Their Fat Using a Natural Protein

Forced expression of the BP3 protein allowed obese mice to reduce their fat mass, despite having a genetic predisposition to eat all the time.

Featured Genetics Open Neuroscience Articles

·April 14, 2018·4 min read

Sweet Tooth Gene Linked to Less Body Fat

Researchers report people with the 'sweet tooth', FGF21 genetic mutation tend to have less body fat. However, the genetic mutation is also linked to slightly elevated blood pressure.

Featured Neuroscience

·November 21, 2017·4 min read

Cinnamon Turns Up the Heat on Fat Cells

A new study reveals the holiday spice cinnamon may be a useful tool in the battle against obesity. Researchers report cinnamaldehyde can improve metabolic health by inducing fat cells to burn energy through a process called thermogenesis.