extracellular matrix

·August 15, 2021·4 min read

Brain Gene Expression Patterns Altered by Chronic Opioid Use

Opioid use disorder affects genes associated with proinflammatory immune molecule encoding and genes associated with remodeling the extracellular matrix, suggesting the connection between neurons may be altered as a result of opioid use. Additionally, those with OUD have higher levels of microglia in the brain.

Featured Neuroscience Open Neuroscience Articles

·July 6, 2020·6 min read

To Let Neurons Talk, Immune Cells Clear Paths Through Brain’s ‘Scaffolding’

Dropping the level of the IL-33 immune molecule increased the number of synapses in the brain. In older mice, ramping up IL-33 helped push the number of new synapses toward a more youthful state.

Electrophysiology Featured Neuroscience

·November 6, 2015·5 min read

How Axons Regenerate on a Proper Path

Researchers have identified key components of a mechanism that allows the nervous system to heal itself.

The image shows different evoked neural signals.

Featured Neuroscience Open Neuroscience Articles

·August 7, 2015·3 min read

Brain Friendly Interface Could Change the Way People with Spinal Cord Injuries Lead Their Lives

Researchers have developed a brain friendly extracellular matrix environment that could help change the way people with spinal cord injury and prosthetics lead their lives.