Examining the impact of eight types of early life stress on the onset of youth-onset depression, researchers found some had little impact on the development of the psychological disorder. Emotional abuse was more strongly associated with the development of major depressive disorder than other early stressors, such as poverty.
Mice that experienced early life stress and later developed irritable bowel syndrome had significantly higher levels of intestinal stem cells and enterochromaffin (EC). Additionally, the mice expressed elevated secretion of serotonin as a result of the increased EC cell density.
Female mice who experienced early life stress developed problems and had fewer neurons in areas of the brain responsible for regulating emotions and making sense of rules, researchers report.
Researchers report stress during fetal development and early childhood can have lasting implications for brain development, leading to increased risks of brain disorders later in life.
A new study reports researchers were able to predict with 80 percent accuracy whether antidepressants would help patients by analyzing their brain function and personal history.
A new study of mice finds early exposure to stress can make specific brain regions mature faster.