A combination of patient-reported subjective cognitive impairment and measurable clinical symptoms, such as amyloid-beta accumulation in the cerebrospinal fluid, may help in the early diagnosis of Alzheimer's disease.
Proteins belonging to the TAM family receptors may be a new biomarker for Alzheimer's disease. The elevated inflammatory markers are conspicuous, even before the onset of dementia.
Some viral infections could increase intercellular spreading of protein aggregates associated with neurodegenerative disorders, increasing the risk for developing Alzheimer's, Parkinson's, and other neurodegenerative diseases.
In the early stages of neurodegenerative diseases, microglia consume glucose to a greater extent than previously believed. The findings may serve as a new biomarker for a range of neurodegenerative disorders.
Researchers say levels of microRNA in the blood may be a reliable new biomarker for diagnosing mild cognitive impairment and other forms of dementia.
Growing up and experiencing stimulating environments throughout life help to keep the hippocampus "young", and can help to preserve mental fitness in old age.
Cardiovascular problems can alter gene activity in the hippocampus, increasing the risk for cognitive decline and memory deficits, a new study reports.
Free radicals help control cellular processes vital for neuroplasticity and neurogenesis in mice.
Young adults with the Alzheimer's associated ApoE gene had differences in brain activity when presented with memory tasks.
A newly designed synthetic compound could act as a prototype for a novel class of drugs to treat neurological damage.
People with subjectively felt memory deficits also exhibited measurable cognitive deficits that were associated with abnormalities in spinal fluid.
In mouse models of Alzheimer's disease, active neurons still encode memory, and a group of active neurons encodes novel environmental information. The signal of the novelty containing neurons causes a superimposition disturbing the signal of memory encoding neurons.
