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Dyrk1A

·April 8, 2026·9 min read

One Compound Repairs Neurons with Autism Mutations

Researchers used a library of 520 FDA-approved drugs and zebrafish "behavioral fingerprints" to identify precision medicine candidates for autism. Levocarnitine emerged as a top drug for reversing symptoms linked to specific risk genes.

Autism Featured Genetics Neuroscience

·April 8, 2021·6 min read

Autism Gene Study Finds Widespread Impact to Brain’s Growth Signaling Network

Mutations in the autism-related Dyrk1a gene lead to brain undergrowth in mice. Researchers say an existing drug appears to reverse the damage.

Image shows neurons in the cerebral cortex.

Featured Genetics

·April 5, 2016·5 min read

Gene Linked to Down Syndrome Associated With Altered Oscillations in Cerebral Cortex

Researchers have identified alterations in neural circuitry that impact cerebral cortex pathology. These alterations could be key to cognitive deficits in Down syndrome.