Trauma-exposed veterans with PTSD and comorbid externalizing psychiatric disorders, such as substance abuse or antisocial personality disorder are at greater risk for early death.
Oxidative damage to telomeres can trigger cellular senescence. The findings could lead to the development of new therapeutics for healthy aging and to combat cancers.
A newly developed blood test can measure the pace of biological aging by identifying specific DNA methylation marks.
Microglia showed DNA methylation profiles that were distinct from other cells in the central nervous system.
Combining two natural products that modulate the epigenome, researchers believe they have identified a feasible approach to reversing symptoms of PTSD in animal models that could be effective in humans.
Simple dietary changes and adopting lifestyle alterations, including improved sleep schedules, taking probiotics, and exercising, can reduce signs of biological aging by three years in just eight weeks, a new study reports.
DNA markers in cells of patients with major depressive disorder appear to be two years older than markers in cells of people without the mental health disorder.
Study sheds light on DNA methylation related to sleep deprivation in those with shift-work disorder.
Twin study reveals how we adapt to aging may be genetically influenced. Individual differences in blood DNA methylation are partly heritable later in life and longitudinally across a decade, researchers report.
Study uncovers DNA hypermethylation is responsible for reduced amygdala volume in male patients with schizophrenia and bipolar disorder.
Marijuana use alters a gene associated with autism in sperm. Hypomethylation was identified in the DLGAP2 gene in the sperm of male rats exposed to THC. The hypomethylated state was also detected in the forebrains of their offspring. Further research is needed to establish if there is a definitive link between paternal cannabis use and ASD in humans.
POMC, a gene which regulates the stress response system, and PER2, a gene associated with circadian regulation, are altered in women who drank moderate-to-high amounts of alcohol during pregnancy and their newborns.
