In older mice, adult neurons in the primary visual cortex with an increased number of "silent synapses" and lacking PSD-95, showed the same structural changes only seen previously in younger animals. Read More
Using a snap-freezing method, researchers have been able to reveal the true structure of the connections that join neurons together in the adult brain. Read More
A clusterization approach allows researchers to analyze dendritic spines in new ways. Read More
Researchers have made an important discovery about the mechanisms behind learning and memory. Depending on the number of synapses, and their proximity, information is processed and stored differently. Read More
Neurons created as a result of adult neurogenesis mature for longer and grow larger than those created during infancy. Findings suggest adult-born neurons may have a more powerful function than those created during infancy and may play a critical role in neuroplasticity. Read More
Computational power is amplified in the brain by newly discovered action potentials in dendrites. Read More
Purkinje cells can modulate and filter incoming signals. The findings shed new light on learning mechanisms within the cerebellum. Read More
Genetic mutations in Usp9X results in the brain growing fewer synapses during development. The mutation also causes hyperactivity and an increased risk of anxiety. The findings shed new light on the cause of autism and other intellectual disabilities. Read More
New memories are laid down via different mechanisms in older mice compared to younger mice. Additionally, synaptic changes linked to new memory formation were harder to modify in older mice. Read More
A lack of oxygen as a result of preterm birth does not cause hippocampal neurons to die but does impair hippocampal development. Hypoxia causes hippocampal cells to fail to mature normally, causing a reduction in long-term potentiation and impaired learning. Read More
From researching the microbiome and immune system to nociception, scientists are looking beyond the nervous system to gain a better understanding of neurological and mental health disorders. Read More
A microscopy study revealed tau controls Fyn clustering in dendrites. The findings shed new light on how certain forms of dementia may occur. Read More
