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dementia

·January 7, 2025·7 min read

New Biomarker Links Brain Waste Clearance to Vascular Dementia

A new study has identified a biomarker, DTI-ALPS, which connects glymphatic system dysfunction to vascular dementia. By analyzing over 3,750 participants, researchers found that lower DTI-ALPS scores correlated with worse executive function, highlighting the glymphatic system's role in clearing brain waste.

This shows people reading in front of a TV and a brain.

Featured Neurology Neuroscience

·December 16, 2024·5 min read

Some Sedentary Activities Are Good For Brain Health

New research highlights that some sedentary activities, like reading or crafting, are better for brain health than others, such as watching TV or gaming. A study of 397 older adults found that mentally stimulating and socially engaging activities support memory and thinking abilities, while passive screen time is linked to cognitive decline.

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·December 6, 2024·5 min read

Antipsychotics Worsen Behavior in Dementia

A study of 500,000 Canadian nursing home residents found antipsychotic medications significantly worsened behaviors in patients, with nearly 68% experiencing increased issues. Antipsychotics are often prescribed "off-label" for dementia-related symptoms, despite serious side effects like tremors and cognitive decline. Researchers advocate for person-centered care, emphasizing non-drug therapies like music, art, and exercise to address behavioral issues.

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·December 4, 2024·3 min read

Study Links Muscle Loss to Alzheimer’s Risk

New research shows that skeletal muscle loss, measured through temporalis muscle size on brain MRIs, is associated with a higher risk of developing Alzheimer’s disease. A study of 621 older adults found that those with smaller temporalis muscles were 60% more likely to develop dementia and experienced greater cognitive and brain volume decline over nearly six years.

Featured Neurology Neuroscience Psychology

·December 3, 2024·3 min read

Empathy Loss in Dementia Linked to Brain Activity Changes

Frontotemporal dementia, affecting about 3% of dementia patients in Sweden, is characterized by a loss of empathy that challenges patients and their families. Using functional MRI, researchers found that patients showed no activation in brain networks associated with empathy when viewing distressing images, unlike healthy individuals.

Featured Neurology Neuroscience

·November 19, 2024·5 min read

Early-Onset Diabetes Linked to Increased Dementia Risk

New research reveals that individuals diagnosed with type 2 diabetes at a younger age face a higher risk of developing dementia, particularly those with obesity. The study found that for each year earlier type 2 diabetes is diagnosed, dementia risk increases by 1.9%.

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·November 12, 2024·5 min read

Frailty Boosts Dementia Risk

Frailty is a strong predictor of dementia risk, with risk increasing by 40% with each 4-5 additional age-related health conditions. This connection between frailty and dementia suggests that frailty may not simply result from undetected dementia but actively contributes to its onset.

Featured Neurology Neuroscience

·November 11, 2024·6 min read

Fluctuating Cholesterol Linked to Higher Dementia Risk

Older adults with significant fluctuations in cholesterol levels are at increased risk for dementia and cognitive decline, even without medication changes. Researchers studied nearly 10,000 older adults, tracking their cholesterol levels and cognitive function over six years. High variability in total and LDL ("bad") cholesterol was associated with a 60% increase in dementia and 23% increase in cognitive decline.

Featured Neurology Neuroscience

·November 1, 2024·5 min read

Socioeconomic Factors Influence Cognitive Health and Dementia Risk

A new study reveals that socioeconomic factors like education, occupation, and wealth play a role in the risk of cognitive impairment and dementia in later life. Tracking over 8,000 adults in England, researchers found that people with higher socioeconomic status were less likely to transition from healthy cognition to impairment and more likely to recover from mild impairment.

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·October 22, 2024·4 min read

Loneliness Increases Dementia Risk by 31%

A large meta-analysis of over 600,000 people shows that experiencing loneliness significantly raises the risk of developing dementia by 31%. Researchers found that loneliness is a key factor in cognitive decline, contributing to conditions like Alzheimer's disease, regardless of age or sex.

Featured Neurology Neuroscience

·October 18, 2024·6 min read

How a Brain Lipid’s Production Could Impact Dementia

Researchers have discovered how a lipid molecule, BMP, crucial for brain function, is produced, potentially opening new doors for treating neurodegenerative diseases like Alzheimer’s and frontotemporal dementia. Two enzymes, PLD3 and PLD4, were found to catalyze the formation of BMP by changing the molecule’s “handedness,” allowing it to remain stable in lysosomes where other lipids are broken down.

Featured Neurology Neuroscience

·October 7, 2024·7 min read

Salience Network Disruption Tied to Dementia Behavior Changes

Researchers have discovered that disruptions in the brain’s salience network, often tied to tau protein buildup, correlate strongly with behavioral changes in people with early-stage dementia. Using advanced brain imaging on 128 participants, they found that as tau impairs this critical network, behavioral symptoms worsen, adding another layer to understanding dementia beyond memory loss.