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Columbia University

This shows a brain made up of clouds and smoke stacks.

·September 6, 2025·8 min read

Air Pollution Linked to Toxic Protein Clumps Driving Lewy Body Dementia

A new study reveals a molecular link between fine particulate air pollution (PM2.5) and Lewy body dementia, a devastating neurodegenerative condition. By combining human epidemiological data and animal experiments, researchers showed that PM2.5 exposure triggers toxic clumps of alpha-synuclein in the brain, similar to those seen in patients.

This shows a pregnant woman in a field surrounded by "danger" signs.

Featured Neuroscience

·August 18, 2025·6 min read

Prenatal Pesticide Exposure Linked to Lasting Brain Damage in Children

A new study provides the strongest evidence yet that prenatal exposure to the insecticide chlorpyrifos (CPF) disrupts brain development, leaving children with structural abnormalities and impaired motor control well into adolescence. Using brain imaging and behavioral assessments of over 270 New York City children, researchers found that higher CPF exposure levels were directly linked to widespread changes in brain structure, function, and metabolism.

Brain Cancer Featured Neuroscience

·August 15, 2025·6 min read

Bacteria and Viruses Join Forces in New Cancer-Killing Therapy

Researchers have developed CAPPSID, a novel cancer therapy that teams bacteria and viruses to infiltrate and destroy tumors. The system hides an oncolytic virus inside Salmonella typhimurium, which naturally migrates into tumors, shielding the virus from immune detection.

This shows a map of the US and a couple behind shattered glass.

Featured Neuroscience Psychology

·August 1, 2025·4 min read

Murder-Suicide Rates in U.S. Higher Than Previously Estimated

New research reveals that murder-suicide incidents in the U.S. are more frequent than previously documented, with an average of 820 related deaths per year. Most incidents involve current or former intimate partners, and nearly all suicides were carried out with firearms.

Featured Neuroscience

·July 2, 2025·5 min read

Aging May Not Equal Chronic Inflammation

A new global study challenges the long-held belief that chronic inflammation is a universal marker of aging. Researchers compared industrialized populations with Indigenous groups and found that "inflammaging" is strongly tied to lifestyle and environmental exposures.

Featured Genetics Neurology Neuroscience

·May 25, 2025·9 min read

ALS Drug Shows Unprecedented Recovery in Patients With Rare Mutation

A groundbreaking experimental therapy for a rare, aggressive form of ALS caused by FUS gene mutations has produced surprising clinical improvements in some patients, including restored mobility and extended survival. The treatment uses antisense technology to silence the FUS gene, reducing toxic protein buildup in motor neurons. Two patients in a recent case series showed remarkable responses—one regained the ability to walk and breathe unassisted, while another has remained symptom-free for three years.

Featured Neuroscience Psychology

·May 7, 2025·8 min read

SSRI Exposure in the Womb May Rewire Brain Circuits

New research suggests that prenatal exposure to SSRIs may alter brain development in ways that increase the risk of depression and anxiety later in life. Using mice and human data, scientists found that early-life SSRI exposure heightened activity in brain fear circuits, a pattern not observed in offspring of depressed mothers who did not take SSRIs.

Featured Neurology Neuroscience

·April 21, 2025·6 min read

Early Alzheimer’s Clues Found in Adults as Young as 24

A new study reveals that cognitive changes tied to Alzheimer's risk factors begin far earlier in life than previously thought, some as early as age 24. Researchers found associations between memory performance and cardiovascular risk factors, immune markers, and Alzheimer’s biomarkers (amyloid, tau, and neurodegeneration) in individuals aged 24–44.

Featured Neurology Neuroscience

·March 3, 2025·6 min read

Sleep Brain Waves Linked to Consciousness in Coma

A new study finds that sleep spindles—bursts of brain activity during sleep—may predict recovery in unresponsive patients with recent brain injuries. Researchers analyzed EEG recordings of 226 comatose patients and found that those with sleep spindles were significantly more likely to regain consciousness and functional independence.

Featured Neuroscience

·February 10, 2025·5 min read

How the Brain Detects Novelty to Predict the Future

A new study shows that the cerebral cortex acts as a "memory machine," constantly detecting novel stimuli to refine its predictions of the future. By imaging the auditory cortex of mice, researchers found that neurons track sensory inputs over time, forming "echoes" that help distinguish new information.

This shows computer generated versions of human cells.

Brain Cancer Featured Genetics Neuroscience

·January 8, 2025·7 min read

AI Reveals Gene Activity in Human Cells

Researchers have developed an AI model that accurately predicts gene activity in any human cell, providing insights into cellular functions and disease mechanisms. Trained on data from over 1.3 million cells, the model can predict gene expression in unseen cell types with high accuracy. It has already uncovered mechanisms driving a pediatric leukemia and may help explore the genome's "dark matter," where most cancer mutations occur.

Featured Genetics Neuroscience

·January 4, 2025·6 min read

New Insight into Genetic Disease Variability

New research reveals that certain cells inactivate one parent’s copy of a gene, leading to a bias in gene activity that may explain why some individuals with disease-causing mutations remain symptom-free. This selective gene inactivation, known as monoallelic expression, affects about 1 in 20 genes and varies between cell types.

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Columbia University

Air Pollution Linked to Toxic Protein Clumps Driving Lewy Body Dementia

Prenatal Pesticide Exposure Linked to Lasting Brain Damage in Children

Bacteria and Viruses Join Forces in New Cancer-Killing Therapy

Murder-Suicide Rates in U.S. Higher Than Previously Estimated

Aging May Not Equal Chronic Inflammation

ALS Drug Shows Unprecedented Recovery in Patients With Rare Mutation

SSRI Exposure in the Womb May Rewire Brain Circuits

Early Alzheimer’s Clues Found in Adults as Young as 24

Sleep Brain Waves Linked to Consciousness in Coma

How the Brain Detects Novelty to Predict the Future

AI Reveals Gene Activity in Human Cells

New Insight into Genetic Disease Variability

PET Tracer Maps Synapse Loss After Spinal Cord Injury

Stress Relief Brain Circuit May Drive Alcohol Relapse

Your Words May Reveal More Than You Think: AI Shows How

How the Brain Uses Objects to Find Direction

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