Using a Brief Negative Symptom Scale (BNSS) to assess negative symptoms of schizophrenia may bridge the gap between clinical interviews and a patient's self-reported measure of symptoms.
Researchers found a positive correlation between glioblastoma cell proliferation and lactate metabolic indicators. Based on this observation, the researchers developed a biomimetic formulation using targeted delivery agents for lactate metabolism-based synergistic therapy against glioblastoma brain cancer.
Researchers have resolved the structures of all 12 serotonin receptor subtypes.
People who display high schizotypal traits are more likely to perceive effort-reward imbalance. Researchers found a link between effort-reward imbalance and reduced gray matter volume, and altered resting-state functional connectivity in those with schizotypal traits.
Amotivation and anhedonia rather than expressive dysfunction play a critical role in determining social functioning in those with schizophrenia.
Researchers have released a whole-brain projectome consisting of over 6,000 single neurons in the mouse prefrontal cortex.
A ventral tegmental area dopamine neuron circuit that projects to the basolateral amygdala selectively controls anxiety-like behaviors, but not depression-like behaviors.
Increased follicle-stimulating hormones following menopause bind to FSHR neurons and activate the C/EBPβ/AEP pathway. The process plays an important role in triggering Alzheimer's pathology in females.