Study reveals the CCR5 gene plays a critical role in linking memories in the brain. The HIV drug maraviroc suppresses the CCR5 gene and may be a potential new treatment to combat memory loss in older adults.
Microglia initially protects the blood-brain barrier from damage due to systemic inflammation. However, microglia can alter their behavior and increase the permeability of the blood-brain barrier, thus damaging it.
Researchers report a protein that affects learning abilities in healthy subjects also plays a role in AIDS related dementia.
