Cannabidiol, or CBD, blocks the ability of lysophosphatidylinositol (LPI) to amplify neural signals in the hippocampus. LPI weakens the signals that counter seizures, further explaining the value of CBD to treat epilepsy.
State-level legalization of recreational cannabis does not increase substance use disorder or encourage the use of other illicit drugs, a new study of twins reveals. Additionally, legalized recreational cannabis can reduce alcohol consumption.
Prenatal exposure to cannabis was associated with an increased risk of neuropsychological disorders, including anxiety and depression, in children. The risk grows as they enter adolescence and adulthood.
Study reports adolescents are three times more likely to develop cannabis use disorder than adults, but may not be at more risk of developing other mental health disorders associated with cannabis use.