Higher levels of immune proteins are present in the blood both before and after an epileptic seizure. Researchers say the biomarkers can be identified via a simple blood test.
A new blood test can detect the GFAP protein at elevated levels in blood samples up to ten years before symptoms of Alzheimer's disease are first noticeable in those with an inherited form of the neurodegenerative disorder.
A new blood test can detect toxic amyloid beta oligomers associated with Alzheimer's disease years before symptoms appear.
Maternal autoantibody–related autism spectrum disorder (MAR ASD) is marked by specific maternal antibodies that react to certain proteins in the fetal brain. Examining the plasma of expecting mothers, researchers found mothers with reactivity to one of the nine MAR ASD patterns were eight times as likely to have a child diagnosed with autism.
Elevated levels of PHGDH in the blood could signal the earliest stages of Alzheimer's disease. Researchers caution older adults against using "brain-boosting" supplements that contain serine due to its link to PHGDH. As PHGDH is a key enzyme in serine production, elevated PHGDH levels results in increased serine levels in the brain.
Measuring blood levels of P-tau181 may allow doctors to diagnose Alzheimer's before the onset of symptoms. Elevated levels of P-tau181 in the blood were associated with greater amyloid beta accumulation in the brain and outperformed two other biomarkers in predicting signs of amyloid beta in brain scans.
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Researchers identified a genetic correlation between blood biomarkers and a range of mental health disorders. The study provides evidence some substance measures within the blood may be involved in the cause of mental illnesses. For example, immune system proteins may be involved in the development of depression, schizophrenia, and anorexia.
Measuring the level of neurofilaments in the blood may be a reliable biomarker for the early diagnosis of ALS.
Researchers identified 15 biomarkers in blood samples that predict the risk of developing depression during pregnancy with 83% accuracy.
A newly developed blood test can measure the pace of biological aging by identifying specific DNA methylation marks.
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A new blood test that uses atomic force microscopy technology appears to be effective as an Alzheimer's diagnostic test.
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Researchers identified 33 metabolic compounds in blood samples that differed between those with dementia and cognitively healthy older adults. 7 of the metabolites were elevated in dementia patients, while 26 were at lower levels compared to samples of those without dementia. Elevating levels of those metabolites could have a neuroprotective effect against dementia.