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          FeaturedGeneticsNeuroscienceOpen Neuroscience ArticlesPsychology
          ·August 29, 2019·3 min read

          Abnormal expression of genes in psychopathy

          Psychopathy is associated with altered expression of genes and immune responses related to molecular pathways. In neurons, the up-regulation of PRL10P9 and ZNF132 and down-regulation of CDG5 and OPRD1 were linked to psychopathic behaviors. The genetic expression explained up to 92% of the variance of psychopathic symptoms. Researchers speculated these genes may be relevant to the lack of empathy and emotional callousness associated with psychopathy, as previous studies have linked a number of these genes to ASD and problematic social behaviors.
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