Discovery concerning the nervous system overturns a previous theory
Rather than having an equal chance of survival, cell death appears to be controlled by a mechanism that filters our the less fit cells.... Read More...
apoptosis
New insight into motor neuron death mechanisms could be a step toward ALS treatment
When a motor neuron-specific pool of heat shock protein 90 (Hps90) was inhibited, motor neuron apoptosis was triggered.... Read More...
Lack of oxygen doesn’t kill infant brain cells, as previously thought
A lack of oxygen as a result of preterm birth does not cause hippocampal neurons to die but does impair hippocampal development. Hypoxia causes hippocampal cells to fail to mature normally, causing a reduction in long-term potentiation and impaired learning.... Read More...
Cell suicide could hold key for brain health and food security
A new study into human and plant cell apoptosis could provide new avenues for the development of treatments for neurodegenerative diseases, and help develop disease-resistant plants.... Read More...
How chronic stress causes brain damage
Chronic stress causes autophagy in adult hippocampal neural stem cells. This results in a decline of hippocampal neurogenesis. Cognitive deficits and mood disorders that arise as a result of chronic stress are a result of autophagic death of hippocampal neural stem cells.... Read More...
Retina restructures itself after cell death
Gene therapy can restore the structure of the retina and regain normal light responses.... Read More...
Certain cells secrete a substance in the brain that protects neurons
Vascular cell loss results in neuron loss, researchers report. However, pericytes secrete a substance that helps protect neurons, even when vascular cell degeneration begins to occur.... Read More...
Experimental PET scan detects abnormal tau protein in brains of living former NFL players
PET imaging of former NFL players who exhibited cognitive decline and psychiatric symptoms linked to CTE showed higher levels of tau in areas of the brain associated with the neurodegenerative disease.... Read More...
Cell death may be triggered by ‘hit-and-run’ interaction
Two different parts to the BAX protein can bind to BH3-only, and these sites function at different stages of BAX activation. When BH3-only binds to one of the regions, BAX becomes able to damage mitochondria. ... Read More...
How light at night may harm outcomes in cardiac patients
Night time white lighting in hospital rooms has been linked to higher rates of inflammation, apoptosis and mortality risk for those who have recently experienced a cardiac event.... Read More...
Brain Discovery Explains A Great Mystery of Alzheimer’s and Parkinson’s
Researchers may have solved one of the great mysteries of neuroscience; namely, why neurons in the temporal lobe are the first to die in Alzheimer's disease, and why dopaminergic neurons are damaged first in Parkinson's. ... Read More...
Immunotherapy Can Be Effective in Treating People with Recurrent Glioblastoma
Researchers report administering immunotherapy treatment prior to surgery for those with recurring glioblastoma brain cancer is more effective that using the treatment after surgery.... Read More...