The STARD7 enzyme helps transport the antioxidant coenzyme Q from the mitochondria to the cell surface.
Diet and exercise can influence hippocampal neurogenesis, researchers say. Poor nutrition and lack of exercise have detrimental effects on hippocampal neurogenesis, increasing the risk for dementia.
Study reveals the molecular clues as to why some neurons are susceptible to death in Alzheimer's disease while others aren't.
FPP, an intermediate in the mevalonate pathway, may trigger cell death in certain situations. The findings shed new light on neurological damage caused by stroke.
Apoptosis plays a critical role in brain development as it influences the thickness of layers in the cerebral cortex, variety, and layer cell density. Alterations in how cells perform division and apoptosis lead to the development of abnormal cortical structures as seen in a variety of neurodevelopmental disorders, including autism.
A nuclear fragment protein activates Xkr4 to display an "eat me" signal to phagocytes.
Researchers have identified a mechanism triggered at neuron birth to intrinsically decrease apoptosis. When the genetic regulation is halted, continuous neuronal survival is disrupted, leading to a decrease in animal survival.
Researchers have mapped the interaction between SARS-CoV-2 proteins and human cells, showing which proteins are being activated and deactivated by coronavirus. The findings reveal how the virus can spread through the human body.
Genetically preventing apoptosis during brain growth allows 'zombie' cells to develop into functioning neurons.
Early birth prompted apoptosis to begin a day early, but delaying the birth did not alter when cell death began to occur. The study suggests birth time has an important and previously unrecognized effect on brain development.
TNFR1 receptors arrange themselves into clusters, joining together trimers and making oligomers that create a pro-inflammatory response observed in a variety of diseases.
Increasing SIRT3 levels with a ketone rich diet may help protect GABAergic interneurons and delay the onset of Alzheimer's disease.
