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apoptosis

·September 5, 2023·5 min read

Iron Buildup Triggers Cell Death in Alzheimer’s

Researchers identified a new form of cell death, termed ferroptosis, in Alzheimer’s disease and vascular dementia. This process involves the destruction of microglia cells—brain immune cells—due to the accumulation of iron.

Featured Neuroscience

·January 30, 2023·3 min read

Antioxidants From Mitochondria Protect Cells From Dying

The STARD7 enzyme helps transport the antioxidant coenzyme Q from the mitochondria to the cell surface.

Featured Neurology Neuroscience

·August 17, 2021·4 min read

Lack of Exercise and Poor Nutrition Could Increase the Risk of Diseases Like Dementia

Diet and exercise can influence hippocampal neurogenesis, researchers say. Poor nutrition and lack of exercise have detrimental effects on hippocampal neurogenesis, increasing the risk for dementia.

Featured Genetics Neurology Neuroscience

·May 6, 2021·6 min read

Why Do Some Neurons Degenerate and Die in Alzheimer’s Disease, but Not Others?

Study reveals the molecular clues as to why some neurons are susceptible to death in Alzheimer's disease while others aren't.

Electrophysiology Featured Neuroscience Open Neuroscience Articles

·April 26, 2021·4 min read

Normally Harmless Cell Molecule Triggers Neuron Death

FPP, an intermediate in the mevalonate pathway, may trigger cell death in certain situations. The findings shed new light on neurological damage caused by stroke.

Featured Neuroscience Open Neuroscience Articles

·March 30, 2021·3 min read

The Early Death of Nerve Cells Is Crucial to Form Healthy Brains

Apoptosis plays a critical role in brain development as it influences the thickness of layers in the cerebral cortex, variety, and layer cell density. Alterations in how cells perform division and apoptosis lead to the development of abnormal cortical structures as seen in a variety of neurodevelopmental disorders, including autism.

This is a cartoon showing the process. See the caption for more information

Featured Genetics Neuroscience

·March 28, 2021·3 min read

Eat Me: The Cell Signal of Death

A nuclear fragment protein activates Xkr4 to display an "eat me" signal to phagocytes.

Featured Genetics Neuroscience

·July 24, 2020·4 min read

Neurons Are Genetically Programmed to Have Long Lives

Researchers have identified a mechanism triggered at neuron birth to intrinsically decrease apoptosis. When the genetic regulation is halted, continuous neuronal survival is disrupted, leading to a decrease in animal survival.

Featured Genetics Neuroscience

·April 10, 2020·4 min read

Mapping SARS-CoV-2 active proteins and how COVID-19 spreads throughout the body

Researchers have mapped the interaction between SARS-CoV-2 proteins and human cells, showing which proteins are being activated and deactivated by coronavirus. The findings reveal how the virus can spread through the human body.

Featured Genetics Neuroscience Open Neuroscience Articles

·March 11, 2020·3 min read

‘Zombie’ brain cells develop into working neurons

Genetically preventing apoptosis during brain growth allows 'zombie' cells to develop into functioning neurons.

Featured Neuroscience

·February 3, 2020·3 min read

Birth timing may affect brain development

Early birth prompted apoptosis to begin a day early, but delaying the birth did not alter when cell death began to occur. The study suggests birth time has an important and previously unrecognized effect on brain development.

Featured Genetics Neurology Neuroscience

·January 15, 2020·3 min read

Inflammation a “game changer” as cellular death dance discovered

TNFR1 receptors arrange themselves into clusters, joining together trimers and making oligomers that create a pro-inflammatory response observed in a variety of diseases.

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apoptosis

Iron Buildup Triggers Cell Death in Alzheimer’s

Antioxidants From Mitochondria Protect Cells From Dying

Lack of Exercise and Poor Nutrition Could Increase the Risk of Diseases Like Dementia

Why Do Some Neurons Degenerate and Die in Alzheimer’s Disease, but Not Others?

Normally Harmless Cell Molecule Triggers Neuron Death

The Early Death of Nerve Cells Is Crucial to Form Healthy Brains

Eat Me: The Cell Signal of Death

Neurons Are Genetically Programmed to Have Long Lives

Mapping SARS-CoV-2 active proteins and how COVID-19 spreads throughout the body

‘Zombie’ brain cells develop into working neurons

Birth timing may affect brain development

Inflammation a “game changer” as cellular death dance discovered

Predicting PTSD: Brain Scans Unravel Trauma’s Long-term Effects

Brain’s Molecular Response to Psychological Loss

Brain’s Dual-Chemical Switch for Attention Revealed

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