APOE proteins were enhanced in the brains of patients with dementia, even when they did not carry the Alzheimer's associated gene.
A new advanced imaging technique shows how cholesterol regulates the production of Alzheimer's associated amyloid beta proteins in astrocytes.
Study reveals the molecular clues as to why some neurons are susceptible to death in Alzheimer's disease while others aren't.
Both the ApoE genotype and the sex of the mouse impacted the manner in which the animals with spinal cord injury responded to hypoxia treatment. Females with the ApoE e4 gene had a negative response to intermittent hypoxia.
Altered pain perception could be a new biomarker to assess late-onset Alzheimer's risk in cognitively healthy individuals with the AopE4 gene before symptoms occur.
An antibody called HAE-4 targets APOE and removes Alzheimer's related amyloid plaques in mouse models. The antibody improves blood vessel function in the brain without raising the risk of brain bleeds.
Young adults with the Alzheimer's associated ApoE gene had differences in brain activity when presented with memory tasks.
Carriers of one copy of the longevity associated klotho gene reduces Alzheimer's risks by 30% for those with genetic risk factors for the neurodegenerative disease.
Frequent exercise, such as walking, swimming, and dancing, was associated with less brain shrinkage in older adults. The effect of exercise in older people was equal to four fewer years of brain aging.
Cognitive performance may predict the progression from normal to abnormal levels of Alzheimer's associated amyloid-beta.
Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS), two atypical parkinsonian syndromes, may be twice as common as previously believed, researchers report.
People with a genetic predisposition for Alzheimer's disease may exhibit changes in memory up-to four decades before the typical age of dementia onset.
