HIV infection leads to increased EIF2 signaling in microglia, astrocytes, and neurons. Study reveals how HIV infection and some antiretrovirals affect cognition and the central nervous system.
Researchers discovered some protease inhibitors used to treat HIV can lead to the production of the peptide amyloid beta.
Researchers report the antidepressant paroxetine suppresses neuroinflammation in improves reaction time in people with HIV associated cognitive impairment.