ALS

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ALS

·October 6, 2020·6 min read

Evidence of Alzheimer’s, Parkinson’s & MND in Brains of Young People Exposed to Dirty Air

An examination of brainstems from children and young adults constantly exposed to air pollution reveals markers of Alzheimer's disease, Parkinson's disease, and motor neuron disease. Findings suggest air pollution poses risks of serious neurological damage from an early age. Read More

Featured Genetics Neurology Open Neuroscience Articles

·September 16, 2020·4 min read

New Gene Implicated in ALS and Other Motor Neuron Diseases

A defective protein quality control system leads to motor neuron death associated with disorders like ALS. Read More

Featured Neurology Neuroscience Open Neuroscience Articles

·September 8, 2020·5 min read

Investigational Drug Stops Toxic Proteins Tied To ALS

c9ASO, an investigational ASO drug, targets the TDP-43 protein, reducing its buildup and decreasing neurological decline associated with ALS and FTD. Read More

Featured Neurology Open Neuroscience Articles

·September 3, 2020·4 min read

Promising New ALS Drug Candidates

Ebselen, a Selenium-based drug molecule, and several other novel compounds can change the characteristics of SOD1. The findings could help with the development of new therapeutics for ALS. Read More

Featured Neurology Neuroscience

·August 26, 2020·5 min read

Newly Discovered ‘Support System’ for Axons Suggests a Novel Therapeutic Target for Neurodegenerative Diseases

A preclinical study reports Schwann cells assist injured axons by releasing protective sugars. The findings have positive implications for the treatment of neurodegenerative diseases like ALS. Read More

Featured Genetics Neurology

·August 20, 2020·5 min read

Autoimmune Diseases in ALS Patients Linked to Genetic Mutation

Study reveals why some people with ALS are prone to developing autoimmune diseases. A genetic mutation that decreases the expression of C9orf72 causes the stimulation of interferon genes (STING) protein to become hyperactive. The hyperactivity leads to increased production of interferons. This can lead to systemic inflammation and the development of autoimmune diseases. Read More

Featured Neurology Neurotech Open Neuroscience Articles

·August 12, 2020·4 min read

Researchers Utilize Human-On-A-Chip Approach to Model ALS Pathology

Human-on-a-chip technology could provide a more valuable clinical-based model for ALS. Read More

Featured Genetics Neurology Neuroscience

·June 10, 2020·4 min read

New genetic defect linked to ALS

Researchers have identified how specific genetic mutations cause ALS. The pathway, they believe, may also be responsible for the development of frontotemporal dementia. Read More

Featured Neurology Neuroscience

·May 21, 2020·2 min read

ALS biomarker found in children’s teeth

Researchers have identified a new, early biomarker for amyotrophic lateral sclerosis (ALS) on the teeth of children. Patients who were diagnosed with ALS in adulthood showed signs of dysregulation uptake of a mixture of essential elements, including zinc, copper, lead, and tin, on their teeth. The study is the first to show clear signatures at birth and within the first decade of life for ALS. Read More

Featured Neurology Neuroscience

·May 15, 2020·4 min read

Gut microbiome influences ALS outcomes

Study reveals a new gut-brain connection in amyotrophic lateral sclerosis (ALS). The gut microbiome could influence the severity of the neurodegenerative disease. Altering the bacteria in the gut may prevent or improve symptoms of ALS. Read More

Featured Neurology Neuroscience

·May 11, 2020·3 min read

Resilience to ALS due to synaptic safety mechanism

Study reveals a self-corrective mechanism within synapses that is activated by neurodegeneration and slows disease progression in animal models of ALS. Read More

Featured Genetics Neurology Neuroscience

·April 20, 2020·5 min read

Researchers delay onset of ALS

Increasing the activity of interneurons in later 5 of the primary motor cortex in mouse models of ALS effectively slowed the onset of the disease. Read More

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