Researchers have discovered how specific brain circuits process empathy, showing that witnessing others in pain activates the same neural pathways as experiencing pain directly. Using advanced imaging techniques, the study pinpointed neurons in the anterior cingulate cortex (ACC) that respond both to personal distress and observed distress in others. The scientists further demonstrated that signals from the ACC to the brain’s periaqueductal gray (PAG) region are crucial for transforming empathy into behavioral responses, like freezing or avoidance.