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addiction

This shows the outline of a stressed person and a brain.

·March 31, 2026·9 min read

Direct Link Between Stress and Addiction Found

Researchers discovered a brain pathway linking stress centers directly to habit regions. While stress normally promotes flexibility, alcohol disrupts this circuit, explaining why stress leads to compulsive drinking and relapse.

Featured Genetics Neuroscience

·March 30, 2026·6 min read

Metabolites “Rewrite” Brain Genes in Addiction

Researchers found that alcohol metabolites directly regulate gene expression in the brain. The ventral hippocampus is especially sensitive to these epigenetic changes, providing a new molecular target for treating alcohol use disorder.

This shows people walking and smoking in an infographic style.

Featured Neuroscience

·March 29, 2026·7 min read

Nicotine Vapes Outperform Patches and Gum for Quitters

A major overview of 14 systematic reviews confirms that nicotine e-cigarettes are more effective for quitting smoking than patches, gum, or behavioral support. Researchers say the evidence is now "clear and consistent."

Featured Genetics Neuroscience Psychology

·March 20, 2026·10 min read

Alcohol, Tobacco, and Opioid Addictions Share Genetic Roots

It’s in the wiring. A massive study reveals that the genetic risk for addiction is mostly shared across all substances and linked to the brain’s "impulse control" center.

This shows a crowd of people and one person with a thought bubble and a bottle inside it.

Featured Neuroscience Psychology

·March 2, 2026·6 min read

Why Socializing Loses to Alcohol in Addiction

New research reveals that activity in the anterior insula primes the brain to choose alcohol over social interaction, offering a new target for addiction treatment.

This shows a brain in a wine glass with a syringe above it. Behind is a strand of DNA.

Featured Neuroscience

·February 21, 2026·7 min read

Mounjaro’s Active Ingredient Slashes Alcohol Intake

From weight loss to sobriety. New research reveals how the active ingredient in Mounjaro "mutes" the brain's reward system to slash alcohol cravings.

This shows a brain with the nucleus accumbens highlighted, showing where the drug activates to prevent opioid relapse behaviors.

Featured Neuroscience Psychology

·February 13, 2026·7 min read

Glaucoma Drug Repurposed to Block Opioid Cravings and Relapse

An old drug for glaucoma might be the key to stopping opioid relapse. New research shows acetazolamide "resets" the brain's reward center to block cravings.

This shows a boy and a girl, and their brains.

Featured Neuroscience

·November 21, 2025·6 min read

Early Brain Activity Differences Predict Addiction Risk in Boys vs Girls

A large-scale analysis of nearly 1,900 children found that those with a family history of substance use disorder show early differences in how their brains transition between activity states, long before any drug exposure. Girls with family history showed increased transition energy in introspective networks, suggesting greater difficulty shifting out of internal, stress-linked states.

This shows a person holding a joint and a glass of scotch.

Featured Neuroscience Psychology

·November 19, 2025·7 min read

Cannabis Blunts Alcohol Cravings

A randomized, placebo-controlled trial shows that cannabis with active THC reduces immediate alcohol cravings and lowers drinking levels in heavy-drinking young adults. After smoking THC, participants not only drank less, they waited longer before taking the first sip and reported lower urges to drink.

This shows a man holding a wine glass against a psychedelic backdrop.

Featured Neuroscience

·November 10, 2025·4 min read

Psychedelics Calm Stress Circuits to Reduce Alcohol Drinking

New research shows that psilocin, the active metabolite of the psychedelic psilocybin, may reduce alcohol consumption by calming stress-sensitive neurons in the central amygdala. In female mice exposed to long-term alcohol use, psilocin dampened the hyperactivity of these neurons, temporarily reducing drinking.

This shows a man and a glass of whiskey.

Featured Genetics Neuroscience

·October 28, 2025·4 min read

Gene That Controls How Sensitive You Are to Alcohol Discovered

Researchers have discovered that a gene called CHRNA3 plays a key role in determining alcohol sensitivity, helping explain why some people tolerate alcohol better than others. When this gene was mutated, subjects were slower to avoid alcohol and consumed more of it, showing reduced sensitivity to its calming effects.

This shows a person running and a brain.

Featured Neuroscience

·September 21, 2025·5 min read

High-Intensity Exercise May Protect Against Cocaine Addiction

A new study shows that high-intensity interval training (HIIT) is more effective than moderate exercise at protecting adolescent lab animals from cocaine use. Animals exposed to HIIT developed a preference for non-drug environments and an aversion to cocaine, linked to increases in ΔFosB, a molecular switch involved in addiction.