Addiction may not always be a fixed personality or genetic trait, instead the result of our plastic brains learning the effect of drugs on our individual responses and the environmental setting in which the substance is used.
A new large-scale genome-wide study has identified 18 new genetic risk factors for opioid use disorder, bringing the number of OUD-associated genes from 1-19.
Study finds a link between the personality trait of perfectionism and severe alcohol use disorder.
The activity of MCH neurons in the lateral hypothalamus during sleep recapitulates REM sleep effects on reducing drug-seeking behaviors.
High-potency cannabis use is associated with an increased risk of addiction, cannabis use disorder, and mental health problems including an increased risk of schizophrenia, a new study reports.
Centralized sensation, or abnormal pain processing in the brain and spinal cord, may be an important underlying factor complicating the treatment of chronic pain in those with opioid use disorder.
Adolescents and young adults who drink alone are at greater risk of developing alcohol use disorder later in life.
Study reports adolescents are three times more likely to develop cannabis use disorder than adults, but may not be at more risk of developing other mental health disorders associated with cannabis use.
Blocking M2Rs muscarinic acetylcholine receptors in the lateral habenula with an experimental drug increased cocaine-seeking behaviors in rat models of impulsive behaviors.
Using lesion network mapping, researchers identified brain circuits associated with addiction remission. The findings provide a new target for the development of treatments for addiction.
Common epigenetic markers associated with food addiction have been identified.
Gene editing could be a potential new treatment for anxiety and alcohol use disorder in adults who indulged in binge drinking as adolescence.
