Neuroscience News - AI, Neuroscience, Psychology Research

·October 24, 2025·4 min read

Brain Circuits Split Food Choices Between Sugar and Fat Cravings

A new study reveals that the brain uses two distinct neural pathways to regulate sugar and fat intake. In mice, glucoprivation—a drop in blood sugar levels—activates separate circuits in the hypothalamus: AMPK-regulated CRH neurons drive high-carbohydrate consumption, while MC4R-expressing neurons promote high-fat food intake.

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·October 24, 2025·7 min read

Alzheimer’s Disrupts Brain’s Internal Clock, Unraveling Gene Rhythms

Alzheimer’s disease not only damages memory but also distorts the brain’s internal clock, disrupting the daily rhythms of hundreds of genes tied to brain health. Researchers found that in mice with amyloid buildup, normal circadian gene activity in microglia and astrocytes—the brain’s immune and support cells—became erratic.

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·October 24, 2025·6 min read

Swap 30 Minutes of Sitting for Light Activity to Boost Next-Day Mood

New research reveals that replacing even 30 minutes of sitting with light physical activity—like walking or doing household chores—can boost mood and energy the following day. The study tracked over 350 young adults using wearable monitors to assess daily movement patterns.

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·October 24, 2025·6 min read

Brain’s Energy Flow Reveals Hidden Coordination During Deep Sleep

New brain imaging research has uncovered how the brain’s energy and activity reorganize as it transitions from wakefulness to deep NREM sleep. Using an advanced tri-modal EEG-PET-MRI approach, scientists found that while cognitive regions quiet down, sensory and motor areas stay active, keeping the brain responsive to the environment.

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·October 24, 2025·9 min read

Gene Editing Reverses Age-Related Memory Loss

Researchers have identified molecular mechanisms behind age-related memory decline — and shown they can be reversed. Two studies revealed that correcting specific molecular processes in the hippocampus and amygdala, and reactivating a silenced memory-supporting gene called IGF2, improved memory in older rats.

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·October 23, 2025·6 min read

Pain Resilience, Not Pain Itself, Predicts How Active People Stay

A new study reveals that how people think about and cope with chronic pain is more important than the pain itself in determining physical activity levels. Researchers found that individuals with higher pain resilience — the ability to maintain positive functioning despite pain — were significantly more active than those with lower resilience.

This shows a teen in bed, awake and looking at a computer late at night.

Featured Neuroscience Psychology

·October 23, 2025·7 min read

Lack of Sleep in Teens Linked to Higher Suicide Risk

Teenagers who sleep less or experience frequent night awakenings are significantly more likely to attempt suicide later in adolescence, according to a major longitudinal study. Researchers analyzed data from more than 8,500 teens and found that poor sleep at age 14 predicted suicide attempts by age 17, even after accounting for other mental health risk factors.

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·October 23, 2025·8 min read

Brain’s Waste System Breakdown Linked to Dementia Risk

Researchers have discovered that problems with the brain’s waste-clearing system—the glymphatic system—may significantly raise the risk of developing dementia. In one of the largest studies to date, MRI data from 40,000 adults revealed that impaired cerebrospinal fluid (CSF) flow predicts dementia risk years before symptoms appear.

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·October 23, 2025·7 min read

Poor Oral Health Linked to Brain Damage Markers

A new study finds that older adults with gum disease are more likely to show signs of white matter damage in the brain — a change tied to memory decline, balance issues, and higher stroke risk. MRI scans revealed that participants with gum disease had significantly more white matter hyperintensities than those without, even after accounting for age and other health factors.

Featured Neurology Neuroscience

·October 22, 2025·8 min read

Oral Bacteria May Drive Multiple Sclerosis

Scientists have found that people with multiple sclerosis (MS) have a distinctly imbalanced oral microbiome—marked by a loss of beneficial bacteria and a rise in inflammation-linked microbes. Using advanced genetic and metabolic profiling, researchers revealed that saliva from MS patients also had lower levels of hypotaurine, a molecule that supports antioxidant defense and nerve health.

Featured Genetics Neurology Neuroscience

·October 22, 2025·8 min read

New AI Tool Reveals Genetic Link Between Memory Cells and Alzheimer’s

A new computational tool developed by researchers has uncovered genetic evidence directly linking Alzheimer’s disease to the loss of memory-making neurons, helping to resolve a decades-long mystery in dementia research. The algorithm, called seismic, matches genetic data to individual cell types, outperforming previous methods and highlighting how specific brain cells—not just immune cells—are implicated in Alzheimer’s.

Featured Neuroscience Psychology

·October 22, 2025·8 min read

Ketamine Fails to Outperform Placebo in Major Depression Trial

A large randomized and blinded clinical trial has found no additional benefit of repeated ketamine infusions over standard inpatient care for treating major depression. The study compared ketamine with a psychoactive placebo and found no meaningful differences in objective or self-reported depression scores, cognition, or quality of life.

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