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mRNA

·June 3, 2023·4 min read

Hitching a Ride: mRNA’s Transport System in Brain Cells Revealed

Researchers made significant advancements in understanding how mRNA is distributed in brain cells. They discovered that a protein complex called FERRY aids Early Endosomes (EEs) to carry mRNAs to distant parts of the neuron.

Featured Genetics Neuroscience Open Neuroscience Articles

·March 8, 2023·4 min read

Modifying Messenger RNA May Provide a New Target for Alzheimer’s Disease

Targeting and reducing the methylation of a key mRNA promoted the migration of macrophages in the brain and can improve cognitive symptoms of Alzheimer's disease.

Featured Genetics Neuroscience

·January 21, 2023·3 min read

Novel mRNA Delivery Method Induces Collagen Repair and Could Replace Fillers for Skin Wrinkles

A novel mRNA delivery method that uses extracellular vesicles initiates collagen replacement in photoaged skin. A single injection increased collagen production and reduced wrinkle formation in targeted areas for two months. Researchers say the new delivery method could be used to treat a number of disorders including ones associated with protein loss associated with aging and hereditary disorders where genes and proteins are missing.

This shows the nanoparticles entering the retina

Featured Genetics Neuroscience Visual Neuroscience

·January 12, 2023·3 min read

A Key Step Toward New Treatment for Hereditary Blindness

Using animal models, researchers demonstrate a potentially effective approach to treating blindness associated with genetic conditions by using mRNA and lipid nanoparticles.

This shows a woman holding her back in pain

Featured Neurology Neuroscience Pain

·October 25, 2022·4 min read

Pain’s Molecular Origins

A new study will explore the genesis of pain on a molecular and cellular level, with the goal of finding new treatments for chronic pain conditions.

This shows a depiction of a brain made up of rainbow colored lines

Featured Genetics Neurology Neuroscience

·April 13, 2022·5 min read

Novel Root Cause of Tau-Induced Neurodegeneration Discovered

mRNA decay may facilitate tau-induced damage to the brain and associated apoptosis that contributes to a range of neurodegenerative disorders. Researchers found the mechanism can be altered pharmacologically, providing a new target for the development of therapeutics to prevent or slow the progression of some neurodegenerative disorders.

Featured Genetics Neuroscience Open Neuroscience Articles

·March 29, 2021·5 min read

Differences in Herpes Virus Symptoms May Relate to Variations in Strain Gene Expression

A new study reveals why some people with the herpes simplex 1 virus experience painful lesions, while others have no symptoms and yet still spread the infection. Researchers say the difference could be a result of how variations in the way certain strains of HSV-1 activate gene expression in neurons.

Events Genetics Neurology Neuroscience

·March 5, 2021·2 min read

mRNA Vaccine Developed to Treat MS-Like Condition in Mice

When injected with the new mRNA vaccine, mice with multiple sclerosis-like symptoms developed less severe symptoms than would normally occur.

Featured Genetics Neuroscience Open Neuroscience Articles

·February 27, 2020·4 min read

Printer toner linked to genetic changes and health risks

Rat model study reveals printer toner nanoparticles may change both genetic and metabolic profiles, making disease more likely.

Featured Neuroscience Psychology

·November 18, 2019·3 min read

Adolescent drinking increases anxiety and alcohol abuse risk later in life

Teenage binge drinking is linked to altered gene expression in the brain, specifically the central nucleus of the amygdala. Adolescent rats exposed to alcohol had increased levels of miR-137, resulting in lower expression of proteins essential for healthy neuron growth. During adulthood, these rats displayed higher levels of anxiety and an increased preference for alcohol consumption.

Featured Genetics Neuroscience

·September 6, 2019·3 min read

Is laziness a choice or genetic trait?

Study identifies a specific gene in rats that relates to physical inactivity. The gene could play a role in human sedentary behaviors.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·September 4, 2019·4 min read

Receptor protein in brain promotes resilience to stress

S1PR3, a receptor found on the surface of brain cells, may play a key role in stress resilience. Veterans with severe PTSD symptoms had lower levels of the S1PR3 protein in their blood than peers without the disorder.

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mRNA

Hitching a Ride: mRNA’s Transport System in Brain Cells Revealed

Modifying Messenger RNA May Provide a New Target for Alzheimer’s Disease

Novel mRNA Delivery Method Induces Collagen Repair and Could Replace Fillers for Skin Wrinkles

A Key Step Toward New Treatment for Hereditary Blindness

Pain’s Molecular Origins

Novel Root Cause of Tau-Induced Neurodegeneration Discovered

Differences in Herpes Virus Symptoms May Relate to Variations in Strain Gene Expression

mRNA Vaccine Developed to Treat MS-Like Condition in Mice

Printer toner linked to genetic changes and health risks

Adolescent drinking increases anxiety and alcohol abuse risk later in life

Is laziness a choice or genetic trait?

Receptor protein in brain promotes resilience to stress

Fumes from Indoor Cooking Fuels Linked to Developmental Delays

Mood Dips During Pill Pause

Visual Recognition Memory: Familiarity Decoded by Brief Spikes

HSN Neuron Unravels Behavior Mysteries

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