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          mRNA

          This shows DNA and a glioblastoma cell.
          Brain CancerFeaturedGeneticsNeurologyNeuroscience
          ·July 29, 2026·8 min read

          Gene Pathway Identified as Glioblastoma Target

          The m6A reader protein IGF2BP3 stabilizes TRNAU1AP mRNA to drive protective selenoprotein synthesis, revealing a novel targeted drug vulnerability in glioblastoma.
          Read More
          This shows a brain.
          Brain CancerFeaturedNeurologyNeuroscience
          ·July 22, 2026·10 min read

          Focused Ultrasound Delivers miRNA to Treat Glioblastoma

          Researchers developed a novel therapeutic approach to combat glioblastoma, the deadliest primary brain cancer.
          Read More
          This shows DNA and a needle.
          Brain CancerFeaturedGeneticsNeurologyNeuroscience
          ·June 18, 2026·7 min read

          Childhood mRNA Cancer Vaccine Reduces Tumors by 70%

          Preclinical trials showed a 70% reduction in tumor size and a 10-to-11-day delay in tumor progression, offering a highly adaptable "Lego-brick" framework for future pediatric cancer immunotherapies.
          Read More
          This shows a pair of glasses and DNA.
          FeaturedGeneticsNeuroscienceVisual Neuroscience
          ·September 26, 2025·5 min read

          mRNA Vaccine Targets Vision Loss in AMD

          A new mRNA vaccine developed in Japan has been shown to suppress abnormal blood vessel growth in the retina of mice, offering hope for patients with age-related macular degeneration (AMD). Current treatments require repeated injections directly into the eye, but this vaccine can be delivered intramuscularly, making it less invasive and easier to administer.
          Read More
          This shows a brain.
          FeaturedGeneticsNeuroscience
          ·February 18, 2025·5 min read

          Nanoparticles Deliver mRNA to the Brain, Bypassing Blood-Brain Barrier

          Scientists have developed a lipid nanoparticle system that enables mRNA to cross the blood-brain barrier, a long-standing challenge in neuroscience. In studies using mice and human brain tissue, these nanoparticles successfully delivered therapeutic mRNA, opening doors for potential treatments for neurological diseases like Alzheimer’s, ALS, and brain cancer.
          Read More
          This shows RNA.
          FeaturedGeneticsNeuroscience
          ·December 17, 2024·6 min read

          Brain-Targeted mRNA Delivery Breaks the Blood-Brain Barrier

          Researchers have developed lipid nanoparticles (LNPs) that cross the blood-brain barrier (BBB) and precisely target brain cells, a major step toward treating neurological diseases like Alzheimer’s. By attaching short peptides to LNPs, scientists achieved targeted mRNA delivery to neurons and endothelial cells, avoiding invasive procedures. Peptides are smaller, more stable, and easier to use than antibodies, making them ideal for LNP-based therapies.
          Read More
          This shows embryonic cells.
          FeaturedGeneticsNeuroscience
          ·May 7, 2024·3 min read

          mRNA Dynamics in Embryonic Cell Identity

          A new study explores mRNA regulation in embryonic development, shedding light on how pluripotent cells specialize. Using single-cell RNA sequencing and metabolic labeling on zebrafish embryos, the research team could distinguish newly synthesized mRNA from maternal contributions.
          Read More
          This shows a neuron.
          FeaturedGeneticsNeuroscience
          ·October 31, 2023·6 min read

          How mRNA Transport Influences Neuronal Health

          Researchers linked the survival and pathology of sensory neurons to mRNA transport within these cells. They focused on the dynein protein complex, specifically the Dynein Roadblock 1 (Dynlrb1) subunit, critical for neuron survival.
          Read More
          This shows mRNA and neurons.
          FeaturedGeneticsNeuroscience
          ·June 3, 2023·4 min read

          Hitching a Ride: mRNA’s Transport System in Brain Cells Revealed

          Researchers made significant advancements in understanding how mRNA is distributed in brain cells. They discovered that a protein complex called FERRY aids Early Endosomes (EEs) to carry mRNAs to distant parts of the neuron.
          Read More
          This shows a brain
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·March 8, 2023·4 min read

          Modifying Messenger RNA May Provide a New Target for Alzheimer’s Disease

          Targeting and reducing the methylation of a key mRNA promoted the migration of macrophages in the brain and can improve cognitive symptoms of Alzheimer's disease.
          Read More
          This shows a drawing of a syringe
          FeaturedGeneticsNeuroscience
          ·January 21, 2023·3 min read

          Novel mRNA Delivery Method Induces Collagen Repair and Could Replace Fillers for Skin Wrinkles

          A novel mRNA delivery method that uses extracellular vesicles initiates collagen replacement in photoaged skin. A single injection increased collagen production and reduced wrinkle formation in targeted areas for two months. Researchers say the new delivery method could be used to treat a number of disorders including ones associated with protein loss associated with aging and hereditary disorders where genes and proteins are missing.
          Read More
          This shows the nanoparticles entering the retina
          FeaturedGeneticsNeuroscienceVisual Neuroscience
          ·January 12, 2023·3 min read

          A Key Step Toward New Treatment for Hereditary Blindness

          Using animal models, researchers demonstrate a potentially effective approach to treating blindness associated with genetic conditions by using mRNA and lipid nanoparticles.
          Read More
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          • Youth Protein TIMP2 Restores Immune Function in the Aging Brain
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          A 3D digital rendering showing a developing fetal brain connected by glowing neural pathways and floating DNA strands, surrounded by subtle immune cells.

          How Severe Illness During Pregnancy Alters Fetal Brain Development

          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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