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          mRNA

          This shows a pair of glasses and DNA.
          FeaturedGeneticsNeuroscienceVisual Neuroscience
          ·September 26, 2025·5 min read

          mRNA Vaccine Targets Vision Loss in AMD

          A new mRNA vaccine developed in Japan has been shown to suppress abnormal blood vessel growth in the retina of mice, offering hope for patients with age-related macular degeneration (AMD). Current treatments require repeated injections directly into the eye, but this vaccine can be delivered intramuscularly, making it less invasive and easier to administer.
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          This shows a brain.
          FeaturedGeneticsNeuroscience
          ·February 18, 2025·5 min read

          Nanoparticles Deliver mRNA to the Brain, Bypassing Blood-Brain Barrier

          Scientists have developed a lipid nanoparticle system that enables mRNA to cross the blood-brain barrier, a long-standing challenge in neuroscience. In studies using mice and human brain tissue, these nanoparticles successfully delivered therapeutic mRNA, opening doors for potential treatments for neurological diseases like Alzheimer’s, ALS, and brain cancer.
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          This shows RNA.
          FeaturedGeneticsNeuroscience
          ·December 17, 2024·6 min read

          Brain-Targeted mRNA Delivery Breaks the Blood-Brain Barrier

          Researchers have developed lipid nanoparticles (LNPs) that cross the blood-brain barrier (BBB) and precisely target brain cells, a major step toward treating neurological diseases like Alzheimer’s. By attaching short peptides to LNPs, scientists achieved targeted mRNA delivery to neurons and endothelial cells, avoiding invasive procedures. Peptides are smaller, more stable, and easier to use than antibodies, making them ideal for LNP-based therapies.
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          This shows embryonic cells.
          FeaturedGeneticsNeuroscience
          ·May 7, 2024·3 min read

          mRNA Dynamics in Embryonic Cell Identity

          A new study explores mRNA regulation in embryonic development, shedding light on how pluripotent cells specialize. Using single-cell RNA sequencing and metabolic labeling on zebrafish embryos, the research team could distinguish newly synthesized mRNA from maternal contributions.
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          This shows a neuron.
          FeaturedGeneticsNeuroscience
          ·October 31, 2023·6 min read

          How mRNA Transport Influences Neuronal Health

          Researchers linked the survival and pathology of sensory neurons to mRNA transport within these cells. They focused on the dynein protein complex, specifically the Dynein Roadblock 1 (Dynlrb1) subunit, critical for neuron survival.
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          This shows mRNA and neurons.
          FeaturedGeneticsNeuroscience
          ·June 3, 2023·4 min read

          Hitching a Ride: mRNA’s Transport System in Brain Cells Revealed

          Researchers made significant advancements in understanding how mRNA is distributed in brain cells. They discovered that a protein complex called FERRY aids Early Endosomes (EEs) to carry mRNAs to distant parts of the neuron.
          Read More
          This shows a brain
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·March 8, 2023·4 min read

          Modifying Messenger RNA May Provide a New Target for Alzheimer’s Disease

          Targeting and reducing the methylation of a key mRNA promoted the migration of macrophages in the brain and can improve cognitive symptoms of Alzheimer's disease.
          Read More
          This shows a drawing of a syringe
          FeaturedGeneticsNeuroscience
          ·January 21, 2023·3 min read

          Novel mRNA Delivery Method Induces Collagen Repair and Could Replace Fillers for Skin Wrinkles

          A novel mRNA delivery method that uses extracellular vesicles initiates collagen replacement in photoaged skin. A single injection increased collagen production and reduced wrinkle formation in targeted areas for two months. Researchers say the new delivery method could be used to treat a number of disorders including ones associated with protein loss associated with aging and hereditary disorders where genes and proteins are missing.
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          This shows the nanoparticles entering the retina
          FeaturedGeneticsNeuroscienceVisual Neuroscience
          ·January 12, 2023·3 min read

          A Key Step Toward New Treatment for Hereditary Blindness

          Using animal models, researchers demonstrate a potentially effective approach to treating blindness associated with genetic conditions by using mRNA and lipid nanoparticles.
          Read More
          This shows a woman holding her back in pain
          FeaturedNeurologyNeurosciencePain
          ·October 25, 2022·4 min read

          Pain’s Molecular Origins

          A new study will explore the genesis of pain on a molecular and cellular level, with the goal of finding new treatments for chronic pain conditions.
          Read More
          This shows a depiction of a brain made up of rainbow colored lines
          FeaturedGeneticsNeurologyNeuroscience
          ·April 13, 2022·5 min read

          Novel Root Cause of Tau-Induced Neurodegeneration Discovered

          mRNA decay may facilitate tau-induced damage to the brain and associated apoptosis that contributes to a range of neurodegenerative disorders. Researchers found the mechanism can be altered pharmacologically, providing a new target for the development of therapeutics to prevent or slow the progression of some neurodegenerative disorders.
          Read More
          This shows neurons
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·March 29, 2021·5 min read

          Differences in Herpes Virus Symptoms May Relate to Variations in Strain Gene Expression

          A new study reveals why some people with the herpes simplex 1 virus experience painful lesions, while others have no symptoms and yet still spread the infection. Researchers say the difference could be a result of how variations in the way certain strains of HSV-1 activate gene expression in neurons.
          Read More
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          This shows a brain.

          Nicotine Withdrawal Makes Smokers More Sensitive to Pain

          This shows a head and a brain.

          PTSD Linked to Accelerated Brain Aging

          This shows a brain with computer components on it.

          Brain Uses AI-Like Computations for Language

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          Extreme Heat Linked to Delays in Early Childhood Development

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