Migraine diagnosis in women prior to pregnancy was linked with an increased risk of complications during pregnancy including preeclampsia, gestational hypertension, and an increased risk of pre-term birth.
Using oral transmucosal delivery of eletriptan hydrobromide delivers faster and more effective relief for migraine sufferers.
A new neuroimaging study identifies migraine sufferers have enlarged perivascular spaces in a brain region called the centrum semiovale.
New abortion bans and restrictions could result in life-threatening consequences for women of childbearing age with epilepsy, multiple sclerosis, and migraine due to restrictions placed on their ability to access life-saving medications. Patients in states with strict abortion restrictions are reporting they are unable to access teratogenic drugs to treat their conditions, including methotrexate, as the medications can induce abortion.
Triptans, drugs commonly prescribed for migraine relief, may be effective for the treatment of obesity. Daily triptan exposure led to reduced food intake and increased weight loss in mouse models.
Valproic acid (VPA), an anti-convulsant medication, can cause birth defects when taken during pregnancy. Researchers identified a molecule called p19Arf that appears to be responsible for VPA's induced senescence in neuroepithelial cells. When exposed to VPA, mice lacking p19Arf did not experience gene expression alterations associated with ASD.
An infusion of the local anesthetic Lidocaine may provide relief to patients with chronic migraines that do not respond to other medications.
Researchers have identified 120 regions of the genome that are connected to migraine risk.
Switching to a diet that includes more leafy greens, including spinach and kale, reduces inflammation and oxidative stress, and improved symptoms associated with chronic migraine.
Those with a genetic predisposition to clinical depression are more likely to exhibit physical symptoms including migraines, chronic pain, and fatigue, researchers report.
Researchers have identified causal genetic links to three blood metabolite levels that increase migraine risks.
Neurovascular dysfunction may explain the link between migraines, hot flashes during menopause, and increased risk of heart disease in women. Researchers found a history of migraines predicted an increase in hot flashes during menopause transition.
