Valproic acid (VPA), an anti-convulsant medication, can cause birth defects when taken during pregnancy. Researchers identified a molecule called p19Arf that appears to be responsible for VPA's induced senescence in neuroepithelial cells. When exposed to VPA, mice lacking p19Arf did not experience gene expression alterations associated with ASD.
An infusion of the local anesthetic Lidocaine may provide relief to patients with chronic migraines that do not respond to other medications.
Researchers have identified 120 regions of the genome that are connected to migraine risk.
Switching to a diet that includes more leafy greens, including spinach and kale, reduces inflammation and oxidative stress, and improved symptoms associated with chronic migraine.
Those with a genetic predisposition to clinical depression are more likely to exhibit physical symptoms including migraines, chronic pain, and fatigue, researchers report.
Researchers have identified causal genetic links to three blood metabolite levels that increase migraine risks.
Neurovascular dysfunction may explain the link between migraines, hot flashes during menopause, and increased risk of heart disease in women. Researchers found a history of migraines predicted an increase in hot flashes during menopause transition.
Study sheds new light on how migraines may occur and why those who are susceptible to migraines see improvements in symptoms as they age.
Pregnant women with a history of migraines are at greater risk of both prenatal and postnatal complications. A new study found migraine sufferers are at increased risk of hyperlipidemia and gestational diabetes during pregnancy, and postnatal depression following the birth of their child.
Four coagulation measures were associated with migraine with aura. These hemostatic factors may have a causal role in migraine with aura.
Findings suggest developing HDAC6 inhibitors could be a novel new therapeutic avenue for the treatment of migraines.
People who use cannabis to help manage the pain associated with chronic migraine are six times more likely to suffer from rebound headaches, or medication overuse headaches, than those who do not use marijuana.