New abortion bans and restrictions could result in life-threatening consequences for women of childbearing age with epilepsy, multiple sclerosis, and migraine due to restrictions placed on their ability to access life-saving medications. Patients in states with strict abortion restrictions are reporting they are unable to access teratogenic drugs to treat their conditions, including methotrexate, as the medications can induce abortion.
Valproic acid (VPA), an anti-convulsant medication, can cause birth defects when taken during pregnancy. Researchers identified a molecule called p19Arf that appears to be responsible for VPA's induced senescence in neuroepithelial cells. When exposed to VPA, mice lacking p19Arf did not experience gene expression alterations associated with ASD.
An infusion of the local anesthetic Lidocaine may provide relief to patients with chronic migraines that do not respond to other medications.
Switching to a diet that includes more leafy greens, including spinach and kale, reduces inflammation and oxidative stress, and improved symptoms associated with chronic migraine.
Researchers have identified causal genetic links to three blood metabolite levels that increase migraine risks.
Neurovascular dysfunction may explain the link between migraines, hot flashes during menopause, and increased risk of heart disease in women. Researchers found a history of migraines predicted an increase in hot flashes during menopause transition.
Study sheds new light on how migraines may occur and why those who are susceptible to migraines see improvements in symptoms as they age.
Pregnant women with a history of migraines are at greater risk of both prenatal and postnatal complications. A new study found migraine sufferers are at increased risk of hyperlipidemia and gestational diabetes during pregnancy, and postnatal depression following the birth of their child.