Unexpected connection between gliomas and neurodegenerative diseases
Study finds significant expression of the Alzheimer's related Tau protein in glioma cells, especially in patients with better prognoses.... Read More...
MAPT
Up to 10,000 people could be living with rare neurological disorders
Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS), two atypical parkinsonian syndromes, may be twice as common as previously believed, researchers report.... Read More...
Genes associated with left-handedness linked with shape of the brain’s language regions
Four genetic regions have been identified as playing a role in left-handedness. Three of the four genes were associated with proteins involved in brain development and structure. Neuroimaging revealed those who were left-handed had increased functional connectivity between left and right language networks. Researchers also found correlations between the genetic regions associated with left-handedness and slightly reduced Parkinson's risk, but a slightly increased risk for schizophrenia.... Read More...
New Genetic Clues to Frontotemporal Dementia
Study reports a mutation in a single gene that causes hereditary frontotemporal dementia makes it harder for neurons to communicate, leading to neurodegeneration.... Read More...
Researchers Pinpoint Genes Tied to Dementia
Researchers have identified two major groups of genes involved in mutations that result in an overproduction of tau. The findings could offer new avenues for treatments to slow the progression of dementia.... Read More...
Zombie Cells Found in Mouse Brains Prior To Cognitive Loss
Researchers report senescent, or Zombie, cells accumulate in certain neurons prior to cognitive loss. By preventing accumulation of these cells, researchers were able to diminish apoptosis, memory loss and tau aggregation.... Read More...
ALS and FTD Share Genetic Link
A new study links common genetic variants to both ALS and frontotemporal dementia. The findings could help in the development of treatment strategies for both disorders, researchers report.... Read More...
Potential Target For Alzheimer’s Treatments
Researchers discover a protein that appears to have an indirect influence on tau proteins. The findings may help in the development of new Alzheimer's treatments.... Read More...
Does Brain Size Really Matter?
Researchers have identified seven genes that predict intracranial volume and Parkinson's disease.... Read More...
Tau Associated MAPT Gene Increases Risk for Alzheimer’s Disease
The findings reported in a new study could help improve the diagnosis and develop new treatments for neurodegenerative diseases such as Alzheimer's and Parkinson's.... Read More...
Rare Genomic Mutations Found in Ten Families with Early-Onset, Familial Alzheimer’s Disease
A new study uncovers unique changes in DNA structure in genes important to neuronal function in relatives with early onset, familial Alzheimer's disease. ... Read More...
Same Genes Linked to Early- and Late-Onset Alzheimer’s Disease
The same gene mutations linked to inherited, early-onset Alzheimer’s disease have been found in people with the more common late-onset form of the illness.T... Read More...