Higher body fat leads to increased atrophy of the brain's gray matter and a greater risk of cognitive decline, researchers report.
Piezo1 limits the potential of regulatory T cells (Treg) to mitigate autoimmune neuroinflammation. Inhibiting Piezo1 could lead to new treatments for autoimmune disorders like multiple sclerosis.
Scars and lesions on the brain and spinal cord offer clues as to why progressive disability occurs in patients with multiple sclerosis.
A new theory proposes an imbalance of blood proteins involved in the immune system and in blood clotting networks leads to inflammation that contributes to the development of psychosis.
Mouse and human studies reveal Interleukin-3 may modify immune responses in the brain that cause cell death and lead to Alzheimer's disease.
Aromatic turmerone, a compound derived from turmeric essential oil, and its derivatives directly affect dopamine neurons to generate neuroprotective properties in tissue culture models of Parkinson's disease.
A diet rich in foods containing isoflavone, a plant-based compound found in legumes, chickpeas, and peanuts, that resembles estrogen, protects against multiple sclerosis symptoms in mouse models.
A diet rich in fermented foods, such as yogurt and kimchi, can help to improve gut microbiome diversity and reduce symptoms of chronic inflammation, a new study reports.
Synthetically optimizing a peptide commonly found in sunflower seeds could help provide relief for gastrointestinal pain and inflammation, a new study reports.
A new study reveals humans and mice have significant differences in how oxidative stress and inflammation trigger immune response genes in astrocytes. Researchers suggest lab models of neurodegeneration should incorporate specially engineered mouse models with lower resistance to oxidative stress, rendering them more human-like.
A Western-style diet, high in omega-6 polyunsaturated fats, increases symptoms of inflammation, neuropathy, and chronic pain. However, changing to a lower-fat diet can help reverse or relieve symptoms of inflammatory pain disorders.
More frequent hospital and doctor's office visits in the years leading up to multiple sclerosis diagnosis with early MS type symptoms are usually associated with a prodromal phase of the disease, when they should be regarded as an ongoing progression of the autoimmune disorder.
