inflammation

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inflammation

·May 22, 2022·3 min read

ATP From Sensory Neuron-Interneuron Crosstalk Is Key to Spreading Inflammation in Rheumatoid Arthritis

In rheumatoid arthritis, inflammation in one joint is transmitted to other joints via the sensory neuron connections in the spinal cord, leading to inflammation in the other joints. Inflammation in one joint led to an increase in ATP in other joints, which triggered an increase of a signaling molecule that resulted in inflammation. Blocking the pathway reduced the spread of inflammation.

Featured Neuroscience

·May 14, 2022·5 min read

Common Fungicide Detected in Pregnant Women and Children

Researchers have detected biomarkers for the common fungicide azoxystrobin (AZ) in the urine of pregnant women and children between the ages of 40-84 months. In mouse models, AZ entered the brains of mice in-utero and killed some embryonic cortical neurons.

Featured Neurology Neuroscience Open Neuroscience Articles Pain

·May 11, 2022·4 min read

Blocking Inflammation May Lead To Chronic Pain

Anti-inflammatories may relieve pain in the short term, but blocking inflammation can lead to longer-term chronic pain, a new study reports.

This shows an older woman sitting on a park bench

Featured Neuroscience

·May 4, 2022·5 min read

Fecal Transplants Reverse Hallmarks of Aging

Transplanting fecal microbiota from young mice to older mice reversed hallmark signs of aging in the gut, brains, and eyes. Transplanting the fecal microbiota from old to young mice had the reverse effect, inducing inflammation in the brain and depleting a key protein associated with healthy vision.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·May 2, 2022·4 min read

Does Autism Begin in the Womb?

Researchers found idiopathic autism occurs as the result of epigenetic abnormalities in hematopoietic cells during fetal development, leading to immune dysregulation in the brain and gut.

Featured Neurology Neuroscience

·April 30, 2022·4 min read

A New Treatment Reduces Inflammation in Multiple Sclerosis Mice Models

Administering a lipid that mediates inflammation reduced chronic inflammation associated with multiple sclerosis in mouse models. Researchers found these mediator lipids are reduced in humans with multiple sclerosis.

This shows the outline of a head and a brain

Featured Neurology Neuroscience

·April 27, 2022·6 min read

How Effects on the Brain Can Produce Long COVID

Immune system mediated injury rather than the virus entering and killing brain cells may explain why people experience long-term consequences associated with COVID-19 infection.

Featured Neuroscience

·April 27, 2022·6 min read

Can Drinking Tea Improve Cognitive Function and Help Prevent Cognitive Decline?

From helping to improve attention and staving off cognitive decline, to improving immune system function, researchers explore the many health benefits tea has to offer.

This shows tissue macrophages in a mouse brain

Featured Genetics Neuroscience

·April 22, 2022·4 min read

New Discoveries About the Origin of the Brain’s Immune System

New findings reveal phagocytes do not fully mature until after birth, contradicting previous assumptions that they mature during embryonic development.

Featured Neuroscience Psychology

·April 20, 2022·4 min read

When Severe Infection Causes Long-Term Mood Disorders

The activation of a neural circuit comprising of the central nucleus of the amygdala and the bed nucleus of the stria terminalis in the first hours following sepsis infection induced anxiety behaviors in mice two weeks after the infection cleared. The behaviors mimicked the PTSD symptoms patients experience following sepsis infection.

Featured Neuroscience Open Neuroscience Articles

·April 18, 2022·5 min read

Vaping Alters Inflammatory State of Brain, Heart, Lungs, and Colon

Daily vaping of pod-based e-cigarettes alters inflammatory states across multiple organs, including the brain. The effects vary depending upon the vape flavors and influence how the body responds to infections. Mint vapes, for example, leave people more sensitive to the effects of bacterial pneumonia than mango flavoring.

Featured Neuroscience Open Neuroscience Articles Psychology

·April 15, 2022·4 min read

Grey Matter Volume Could Inform Treatment Decisions for Developing Mental Health Disorders

Lower gray matter volume in the brain is indicative of a higher risk of developing mental health disorders including depression and psychosis. However, those with slightly greater gray matter volume were more likely to recover from their disorders. Researchers believe reduced gray matter volume may be linked to higher levels of inflammation, reduced concentration, and other cognitive impairments associated with disorders like schizophrenia.

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