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HIV

·May 8, 2025·4 min read

HIV Drugs Linked to Lower Alzheimer’s Risk

New research shows that HIV drugs called NRTIs may significantly reduce the risk of developing Alzheimer’s disease. Analyzing two large health databases, scientists found that patients on NRTIs had a 6% to 13% annual decrease in Alzheimer’s risk.

Featured Neurology Neuroscience

·April 16, 2024·5 min read

HIV Drugs May Reduce Alzheimer’s Risk

Common HIV drugs could reduce the incidence of Alzheimer’s disease (AD). Utilizing anonymized prescription data from over 225,000 individuals, the study found that HIV-positive patients taking reverse transcriptase (RT) inhibitors showed a significantly lower rate of AD compared to the general population.

This shows a peron's hands and the HIV virus structure.

Featured Genetics Neuroscience

·May 25, 2023·8 min read

Stem Cell Transplants May Cure HIV

Researchers reveal two nonhuman primates were cured of Simian Immunodeficiency Virus (SIV), the monkey form of HIV, after a stem cell transplant. The team identified two circumstances that must coincide for a cure to occur and tracked the sequence in which HIV is cleared from the body. The insights may help develop a widespread cure for HIV, which affects around 38 million people globally.

Featured Neuroscience Psychology

·January 6, 2023·4 min read

Women Experiencing Intimate Partner Violence Three Times More Likely to Contract HIV

Study reveals women who experience domestic abuse are three times more likely to contract HIV infection.

Featured Neurology Neuroscience

·June 2, 2021·8 min read

How HIV Infection Shrinks the Brain’s White Matter

HIV infection prevents myelin-associated oligodendrocytes from maturing, this, in turn, hampers white matter production in the brain.

Featured Neurology Neuroscience

·March 29, 2021·4 min read

Chronic Viral Infections Can Have Lasting Effects on Human Immunity, Similar to Aging

Chronic viral infections have a profound and lasting impact on the immune system in a similar way to aging. Chronic inflammation that occurs as a result of immune system dysregulation is often seen in diseases associated with aging.

This is an image of the brain from the study

Featured Neurology Neuroscience Open Neuroscience Articles

·January 15, 2021·6 min read

Study Measures Brain Volume Differences in People With HIV

Lower white blood cell count associated with HIV infection was linked to decreased volume in the hippocampus and thalamus.

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·June 13, 2020·4 min read

Brain cells can harbor and spread HIV virus to the body

Astrocytes harbor HIV and spread the virus to CD4+ T cells that traffic the virus out of the brain and into other organs. HIV moves via this route, even when the virus is suppressed with cART.

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·March 27, 2020·7 min read

A new way to study HIV’s impact on the brain

HIV infection leads to increased EIF2 signaling in microglia, astrocytes, and neurons. Study reveals how HIV infection and some antiretrovirals affect cognition and the central nervous system.

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·July 16, 2019·3 min read

Persistent HIV in central nervous system linked to cognitive impairment

HIV can persist in the nervous system, even when the virus is suppressed. Even when the virus is suppressed, neurocognitive problems associated with the infection can persist.

Featured Neuroscience

·July 8, 2019·4 min read

Two new algorithms can identify patients at risk of HIV

A new machine learning algorithm automatically selected important risk-related variables of HIV from millions of medical records. The algorithm can detect those most vulnerable to HIV infection and could play an important role in increasing the prescription of preexposure prophylaxis medications to prevent infection.

Featured Neurology Neuroscience Open Neuroscience Articles

·June 29, 2019·4 min read

Newly discovered immune cells at the frontline of HIV infection

A newly discovered subset of dendritic cells have been implicated in sexually transmitted HIV infection. The CD11c+ dendritic cells are found in human genital tissue at the epithelial level. They are the first immune cells to interact with the HIV virus. The cells directly transfer the virus to CD4 T cells, making them key drivers in HIV transmission.