FeaturedNeurologyNeuroscience·April 16, 2024·5 min readHIV Drugs May Reduce Alzheimer’s RiskCommon HIV drugs could reduce the incidence of Alzheimer’s disease (AD). Utilizing anonymized prescription data from over 225,000 individuals, the study found that HIV-positive patients taking reverse transcriptase (RT) inhibitors showed a significantly lower rate of AD compared to the general population.Read More
FeaturedGeneticsNeuroscience·May 25, 2023·8 min readStem Cell Transplants May Cure HIVResearchers reveal two nonhuman primates were cured of Simian Immunodeficiency Virus (SIV), the monkey form of HIV, after a stem cell transplant. The team identified two circumstances that must coincide for a cure to occur and tracked the sequence in which HIV is cleared from the body. The insights may help develop a widespread cure for HIV, which affects around 38 million people globally.Read More
FeaturedNeurosciencePsychology·January 6, 2023·4 min readWomen Experiencing Intimate Partner Violence Three Times More Likely to Contract HIVStudy reveals women who experience domestic abuse are three times more likely to contract HIV infection.Read More
FeaturedNeurologyNeuroscience·June 2, 2021·8 min readHow HIV Infection Shrinks the Brain’s White MatterHIV infection prevents myelin-associated oligodendrocytes from maturing, this, in turn, hampers white matter production in the brain.Read More
FeaturedNeurologyNeuroscience·March 29, 2021·4 min readChronic Viral Infections Can Have Lasting Effects on Human Immunity, Similar to AgingChronic viral infections have a profound and lasting impact on the immune system in a similar way to aging. Chronic inflammation that occurs as a result of immune system dysregulation is often seen in diseases associated with aging.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·January 15, 2021·6 min readStudy Measures Brain Volume Differences in People With HIVLower white blood cell count associated with HIV infection was linked to decreased volume in the hippocampus and thalamus.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·June 13, 2020·4 min readBrain cells can harbor and spread HIV virus to the bodyAstrocytes harbor HIV and spread the virus to CD4+ T cells that traffic the virus out of the brain and into other organs. HIV moves via this route, even when the virus is suppressed with cART.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·March 27, 2020·7 min readA new way to study HIV’s impact on the brainHIV infection leads to increased EIF2 signaling in microglia, astrocytes, and neurons. Study reveals how HIV infection and some antiretrovirals affect cognition and the central nervous system.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·July 16, 2019·3 min readPersistent HIV in central nervous system linked to cognitive impairmentHIV can persist in the nervous system, even when the virus is suppressed. Even when the virus is suppressed, neurocognitive problems associated with the infection can persist.Read More
FeaturedNeuroscience·July 8, 2019·4 min readTwo new algorithms can identify patients at risk of HIVA new machine learning algorithm automatically selected important risk-related variables of HIV from millions of medical records. The algorithm can detect those most vulnerable to HIV infection and could play an important role in increasing the prescription of preexposure prophylaxis medications to prevent infection.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·June 29, 2019·4 min readNewly discovered immune cells at the frontline of HIV infectionA newly discovered subset of dendritic cells have been implicated in sexually transmitted HIV infection. The CD11c+ dendritic cells are found in human genital tissue at the epithelial level. They are the first immune cells to interact with the HIV virus. The cells directly transfer the virus to CD4 T cells, making them key drivers in HIV transmission.Read More
FeaturedNeurosciencePsychology·April 3, 2019·2 min readOpioid epidemic is increasing rates of some infectious diseasesThe opioid epidemic is fueling a surge in infectious diseases such as HIV, hepatitis and soft tissue infections, researchers report.Read More