The protein tubulin blocks molecules that trigger the production of cAMP, leading to reduced messaging in the brain. Previous studies have found those with depression have less cAMP in their brains. The findings suggest tubulin could be a potential biomarker for depression. Read More
Environmental light has been shown to affect traumatic long-term memory retention in Drosophila. Read More
Mouse study reveals a gene that influences memory recall at different times of the day. Researchers identified how the gene causes mice to be more forgetful just before they normally wake. Read More
A mechanism that links exposure to high-fat diets in mice to changes in hypothalamic function which leads to depression has been identified. Saturated fatty acids enter the brain via the bloodstream, where they accumulate and affect key signaling pathways associated with the development of depression. Read More
Researchers explore the mechanisms behind ketamine's effectiveness at treating depression. The study reports the long lasting effects of ketamine may be due to G proteins timing in moving back to lipid rafts. Read More
Study reveals how the mechanism for storing olfactory memories differs slightly from erasing unnecessary memories. Understanding how the brain gets rid of unimportant memories could help unlock new avenues of research to better understand memory loss in aging, researchers say. Read More
Hordenine, a substance present in beer and malted barley, activates dopamine D2 receptors through G proteins, leading to a possibly prolonged effect on the brain's reward center, researchers report. Read More
Researchers have identified a compound that appears to enhance long term memory. Read More
A new study reveals animals injected with caffeine during the last 10 minutes of exposure to general anesthetic woke more quickly than those injected with saline solution. Waking times became significantly quicker with higher doses of caffeine. Read More
Researchers have discovered 24 compounds, including caffeine, that have the potential to boost NMNAT2, an enzyme shown to help protect against dementia. Read More
A new study explores how neural activity influences CREB dynamics. Read More
Researchers report a protein normally associated with prion diseases may help to maintain myelin. Read More