Neural networks play a key role in regulating circadian rhythms through the mediation of cAMP. The findings may help with developing new strategies to manage circadian rhythm problems such as sleep disorders.
Researchers identified a new mechanism by which auditory sensitivity is regulated. The mechanism can temporarily reduce sensitivity in the auditory system to protect itself from loud sounds that can cause hearing damage.
The protein tubulin blocks molecules that trigger the production of cAMP, leading to reduced messaging in the brain. Previous studies have found those with depression have less cAMP in their brains. The findings suggest tubulin could be a potential biomarker for depression.
A mechanism that links exposure to high-fat diets in mice to changes in hypothalamic function which leads to depression has been identified. Saturated fatty acids enter the brain via the bloodstream, where they accumulate and affect key signaling pathways associated with the development of depression.
Researchers explore the mechanisms behind ketamine's effectiveness at treating depression. The study reports the long lasting effects of ketamine may be due to G proteins timing in moving back to lipid rafts.
Study reveals how the mechanism for storing olfactory memories differs slightly from erasing unnecessary memories. Understanding how the brain gets rid of unimportant memories could help unlock new avenues of research to better understand memory loss in aging, researchers say.
A new study reveals animals injected with caffeine during the last 10 minutes of exposure to general anesthetic woke more quickly than those injected with saline solution. Waking times became significantly quicker with higher doses of caffeine.