Latest

BMAL1

·October 27, 2020·4 min read

How a Common Mutation Leads to ‘Night Owl’ Sleep Disorder

A mutation in a gene associated with circadian rhythm extends the clock period, causing people to stay up late at night and sleep late in the mornings.

Featured Genetics Neuroscience

·February 19, 2020·4 min read

Bmal1 gene is not an essential regulator of circadian rhythms

Deleting the circadian rhythm-associated BMAL1 gene in animal models, researchers discovered tissue continued to follow a 24-hour rhythm, even in the absence of external stimuli that can influence the cycle.

Featured Genetics Neuroscience Open Neuroscience Articles

·January 7, 2020·4 min read

Removing body clock gene protects mice against pneumonia

Removing BMAL1, a gene commonly associated with circadian rhythm, makes macrophages more effective and the body more resistant to pneumonia.

This shows the researcher next to a head made of clocks

Featured Neuroscience

·May 30, 2019·3 min read

Body parts respond to day and night independently from brain

Skin and liver cells appear to have their own circadian clock. Both the liver and skin respond to changes in light and maintain critical function, independent of the brain's circadian rhythm.

These are two of the baby clone monkeys.

Featured Genetics Neuroscience Neuroscience Videos Open Neuroscience Articles

·April 11, 2019·5 min read

Gene-edited disease monkeys cloned in China

Researchers in China successfully used CRISPR gene editing to produce five monkey clones from the fibroblasts of a donor monkey with disease phenotypes.

Featured Genetics Neuroscience Open Neuroscience Articles

·January 15, 2019·3 min read

How Fasting Can Improve Overall Health

Researchers report fasting affects the circadian rhythm of the liver and skeletal muscles, allowing them to rewire their metabolism. The study suggests fasting can help improve health and protect against aging related diseases.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·August 21, 2018·4 min read

How the Body Clock Controls Inflammation

A new study sheds light on how the circadian clock controls inflammatory response. By understanding the link between inflammation and circadian rhythm, researchers believe it may be most effective to target specific conditions at certain times of the day. The findings may also explain why those who experience body clock disruptions are more susceptible to inflammatory conditions.

Brain Cancer Featured Genetics Neurology Neuroscience

·December 28, 2017·5 min read

Cancer Overrides the Circadian Clock to Survive

A new study reports misfolded proteins can cause circadian rhythm disruptions which contribute to cancerous tumor growth.

Image shows a woman surrounded by clocks.

Featured Genetics Neurology Open Neuroscience Articles

·December 12, 2017·3 min read

Time of Day Affects Severity of Autoimmune Disease

Researchers shed light on how the circadian rhythm and time of day impact immune response in autoimmune diseases. The findings could help in the development of new treatments to tackle a range of autoimmune disorders.

Featured Neuroscience

·August 12, 2017·5 min read

Sleep Biology Discovery Could Lead to New Insomnia Treatments That Don’t Target the Brain

According to researchers, increasing levels of Bmal1 in the skeletal muscles of mice makes the animals resistant to insomnia and sleep deprivation. The findings could provide a new treatment target for sleep disorders.

Featured Neuroscience

·August 4, 2017·2 min read

Muscle, Not Brain, May Hold Answers to Some Sleep Disorders

A new study reveals mice with higher levels of BMAL1 in their muscles were able to recover from sleep deprivation more quickly than those with the protein removed.