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Alzheimer’s disease

·July 11, 2024·4 min read

Study Reveals Structure of Alzheimer’s Molecules in Human Brain

In a groundbreaking study, scientists have determined the structure of molecules within a human brain affected by Alzheimer’s disease. Using cryo-electron tomography and fluorescence microscopy, researchers created 3D maps of proteins like β-amyloid and tau, which cause dementia.

Featured Neurology Neuroscience

·July 11, 2024·3 min read

Predicting Cognitive Decline in Early Alzheimer’s

A new study predicts cognitive decline rates in people with early Alzheimer's and explores how new drugs may slow this process. Researchers found that prediction models can estimate the rate of decline but with some uncertainty. These models could eventually help answer practical questions about quality of life for patients. The findings highlight the potential of new treatments to delay cognitive impairment.

Featured Neuroscience

·June 28, 2024·5 min read

Serotonin 2C Receptor Key to Memory

Researchers discovered the serotonin 2C receptor in the brain plays a crucial role in regulating memory in both humans and animal models. This breakthrough offers insights into conditions associated with memory loss, such as Alzheimer’s disease, and suggests new treatment pathways.

Featured Genetics Neurology Neuroscience

·June 28, 2024·4 min read

New Molecular Signatures Found for Alzheimer’s Disease

Researchers identified unique molecular signatures of blood-brain barrier dysfunction in Alzheimer's disease. They discovered altered communication between brain vascular cells mediated by VEGFA and SMAD3 molecules. These findings could lead to new diagnostic biomarkers and treatment options for Alzheimer's.

Featured Neurology Neuroscience

·June 25, 2024·7 min read

AI Model Predicts Alzheimer’s Using Speech Analysis

can predict whether someone with mild cognitive impairment will develop Alzheimer's disease with 78.5% accuracy by analyzing speech. This tool could enable earlier diagnoses and more accessible cognitive impairment screening without expensive tests. The model uses machine learning to evaluate speech content, offering a non-invasive way to monitor dementia risk. Further research aims to improve and expand this technology.

This shows an older man and a brain scan.

Featured Neurology Neuroscience

·June 21, 2024·4 min read

Ozempic May Reduce Alzheimer’s Risk

GLP-1 agonists like Ozempic reduce the risk of dementia in type 2 diabetes patients. The research followed over 88,000 individuals for up to ten years, showing a 30% lower risk compared to sulfonylureas and a 23% lower risk compared to DPP-4 inhibitors. These findings can guide doctors in selecting medications for older diabetes patients. However, further randomized trials are needed to confirm these results.

Featured Neurology Neuroscience

·June 21, 2024·8 min read

Synthetic Peptide Reverses Alzheimer’s Symptoms

Researchers reversed Alzheimer's symptoms in mice using a synthetic peptide, PHDP5, that targets brain function. The study shows that PHDP5 can cross the blood-brain barrier and restore memory by improving synaptic function. The treatment could delay cognitive decline if administered early. This breakthrough paves the way for new Alzheimer's therapies focusing on brain structure and function.

Featured Genetics Neurology Neuroscience

·June 17, 2024·6 min read

Maternal Alzheimer’s: A Risk Factor for Brain Changes

A new study finds that inheriting Alzheimer's risk from your mother, regardless of her age at onset, is linked to increased amyloid levels in the brain. This protein is a hallmark of Alzheimer's disease. The findings suggest maternal history of memory impairment, even without a formal diagnosis, could be a crucial factor in identifying individuals at risk of Alzheimer's.

Featured Neurology Neuroscience

·June 10, 2024·2 min read

FDA Panel Backs Donanemab: New Hope for Early Alzheimer’s Treatment

Eli Lilly’s Alzheimer’s drug, Donanemab, has been recommended for FDA approval by an independent panel. The drug has shown promise in slowing early-stage Alzheimer’s, despite risks like brain swelling. This recommendation follows a prior FDA rejection due to insufficient data. If approved, Donanemab could revolutionize Alzheimer's treatment, offering new hope for patients and their families.

This shows blue pills in an old man's hand.

Featured Neurology Neuroscience

·June 8, 2024·4 min read

Viagra Shows Promise in Boosting Brain Blood Flow for Dementia Prevention

A new study reveals that sildenafil (Viagra) enhances brain blood flow and improves blood vessel function in patients at risk of vascular dementia. This study marks a significant advancement in addressing this condition. The team found that sildenafil increased blood flow in the brain's small and large vessels, potentially preventing dementia. These findings highlight the drug's promise for larger-scale trials to confirm its effectiveness.

Featured Neurology Neuroscience

·June 6, 2024·5 min read

MRI Method Predicts Dementia 9 Years in Advance with 80% Accuracy

Researchers developed a method to predict dementia with over 80% accuracy up to nine years before diagnosis. Using fMRI scans, the team analyzed changes in the brain's default mode network (DMN), which is affected early in Alzheimer's disease. This approach outperforms traditional memory tests and brain shrinkage measurements. The study used data from over 1,100 volunteers and highlights potential applications for early intervention.

Featured Neurology Neuroscience

·May 31, 2024·3 min read

Ketones May Help Reverse Cognitive Decline

As we age, our brain naturally becomes more insulin resistant, disrupting neuron communication and leading to cognitive decline and neurodegeneration. Researchers studied how acute insulin resistance impacts neuronal function before symptoms of chronic conditions like Alzheimer's manifest.

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Alzheimer’s disease

Study Reveals Structure of Alzheimer’s Molecules in Human Brain

Predicting Cognitive Decline in Early Alzheimer’s

Serotonin 2C Receptor Key to Memory

New Molecular Signatures Found for Alzheimer’s Disease

AI Model Predicts Alzheimer’s Using Speech Analysis

Ozempic May Reduce Alzheimer’s Risk

Synthetic Peptide Reverses Alzheimer’s Symptoms

Maternal Alzheimer’s: A Risk Factor for Brain Changes

FDA Panel Backs Donanemab: New Hope for Early Alzheimer’s Treatment

Viagra Shows Promise in Boosting Brain Blood Flow for Dementia Prevention

MRI Method Predicts Dementia 9 Years in Advance with 80% Accuracy

Ketones May Help Reverse Cognitive Decline

Great Apes’ Gaze Reveals Human-Like Event Perception

When Do Kids Start Creating Original Sentences? AI Pinpoints the Age

How Memories Shape Decisions and Future Well-Being

Alzheimer’s Drug Shrinks Brain Volume by Removing Amyloid Plaques

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