Financially Exploited Seniors Show Brain Differences and Are More Frail

Summary: Older adults who experienced financial exploitation showed differences in brain activity in areas associated with social judgment and decision making. Additionally, those who are exploited financially tend to be physically frailer than their peers, with particular deficits in vision and hearing.

Source: USC

Scams and fraud exact a heavy toll on older adults, with estimates of yearly losses ranging from $3 billion to $36 billion in the U.S. alone.

Lasting damage can occur. Because many seniors live off of resources accumulated across their working lifetimes, such as retirement savings, victims may be unable to recoup what’s taken from them. Considering the additional impact on family members and caretakers, financial exploitation in this growing demographic is a significant public health concern.

Two recent studies led by USC provide new insight into the little-studied question of which factors put older adults at risk for financial exploitation.

One, published in Frontiers in Aging Neuroscience, is only the second brain imaging study to center on financial exploitation in older adults. The scientists found that those who report being financially exploited show differences in the activity of brain regions tied to decision-making and social judgments compared to those without a history of financial exploitation.

The other, which appears in Gerontology and Geriatric Medicine, is the first study to focus specifically on the relationship between financial exploitation and frailty in older adults. The findings showed that those who reported being financially exploited are frailer physically — with particular deficits in vision and hearing — compared to their peers.

The papers come out of the Finance, Cognition, and Health in Elder Study at USC, which enrolls participants who are 50 years and older with no history of dementia. It is led by Duke Han, senior author on both publications and professor of family medicine, neurology, psychology and gerontology in the Keck School of Medicine of USC.

“Ultimately, we want older adults to experience all the best in life, to hold onto their wealth and to live life well into old age,” said Han, who is also director of neuropsychology in the USC Department of Family Medicine. “It crushes us to see them financially exploited. However, not all older adults are at risk for financial exploitation, and we want to try to predict which people might be more at risk.”

Brain differences correlate with falling victim to fraud

The Frontiers in Aging Neuroscience study used magnetic resonance imaging to examine neurological co-activity. Han and his colleagues compared 16 older adults who reported experiencing financial exploitation with 16 who did not, studying their brains while in a resting state. The scientists delved into functional connectivity — in other words, which brain regions activate at the same time.

Functional connectivity can serve as a sort of canary in the coal mine, signaling changes that come with age-related diseases, including Alzheimer’s, before alterations to structures in the brain are detectable.

The research team focused in on three areas of the brain tied to making decisions and evaluating social situations. The study demonstrated subtle but significant differences between connectivity in these regions among those who reported financial exploitation compared to the control group:

  • The medial frontal cortex, which is a seat of executive functioning in the brain
  • The hippocampus, which is tied to remembering specific events and envisioning future scenarios
  • The insula, which is associated with evaluating the trustworthiness of people or situations

“It makes sense that the ability to project a future self through the hippocampus and the ability to assess trustworthiness through the insula might be implicated in financial exploitation risk,” Han said.

However, he emphasizes that the current study indicates correlation rather than causation. To zero in on cause and effect, a larger study that follows participants over time is necessary. Han is currently seeking federal grant funding to pursue such a study.

Problems seeing and hearing may put seniors at risk

For the Gerontology and Geriatric Medicine research, Han and his team employed a widely used questionnaire for identifying frailty to compare 24 seniors who reported financial exploitation with 13 peers who hadn’t experienced it. The assessment asked about physical issues including fatigue, difficulty walking and poor hearing or vision; psychological issues such as anxiety and problems remembering; and social issues such as isolation and loneliness.

The participants who had experienced financial exploitation reported being significantly frailer than the control group, with that difference showing up on the physical scale but not the measures of psychological or social frailty. Specifically, they reported significantly poorer hearing and marginally poorer sight.

Although this study dealt in correlations, Han notes that it’s unlikely that financial exploitation leads to hearing or vision loss.

This shows an older lady
The scientists found that those who report being financially exploited show differences in the activity of brain regions tied to decision-making and social judgments compared to those without a history of financial exploitation. Image is in the public domain

“The methods that scammers and fraudsters use put a stress on being able to see and hear things accurately,” he said. “It stands to reason that this would actually be a mechanism for how certain older adults might be more vulnerable to financial exploitation.”

The researchers hope to build on these findings to conduct a larger study that investigates whether measures such as the use of hearing aids and properly calibrated corrective lenses provide protection against financial exploitation.

“This research really does point to the importance of regular visits with a doctor and keeping up on your hearing and vision,” Han said. “If we can confirm the clinical relevance and then get the word out that the more you address sensory functioning, the more it potentially protects you against financial exploitation, then all the better.”

The first author of the Frontiers in Aging Neuroscience study is Gali Weissberger, a former postdoctoral scholar from Han’s lab at the Keck School of Medicine. Other authors are Dr. Laura Mosqueda, Annie Nguyen, Jenna Axelrod and Caroline Nguyen, all of the Keck School; Patricia Boyle of Rush University Medical Center; and Nathan Spreng of McGill University in Canada.

Axelrod, a postdoctoral scholar from Han’s research group, is the first author of the Gerontology and Geriatric Medicine paper. The Keck School’s Dr. Mosqueda, Weissberger, Nguyen and Emanuil Parunakian were co-authors, along with Boyle from Rush University.

Funding: Both studies were supported by the Elder Justice Foundation, the Cathay Bank Foundation, the National Institute on Aging (T32-AG000037) and the USC Department of Family Medicine.

About this aging research news

Source: USC
Contact: Laura LeBlanc – USC
Image: The image is in the public domain

Original Research: Open access.
Functional Connectivity Correlates of Perceived Financial Exploitation in Older Adults” by Gali Weissberger et al. Frontiers in Aging Neuroscience.

Open access.
Frailty and Perceived Financial Exploitation: Findings from the Finance, Cognition, and Health in Elders Study” by Frailty and Perceived Financial Exploitation: Findings from the Finance, Cognition, and Health in Elders Study” et al. Gerontology and Geriatric Medicine


Functional Connectivity Correlates of Perceived Financial Exploitation in Older Adults

Financial exploitation (FE) in old age is devastating and common; however, the neural correlates of FE are poorly understood. Previous studies of FE in older adults have implicated declines in decision making and social cognition as two risk factors for FE in later life. Here we examined whether functional connectivity among brain regions implicated in decision making and social cognition differed for those with an experience of FE vs. those without. Participants included 16 older adults without cognitive impairment who reported FE (Mean age = 70.5, 62.5% female, Mean education = 16.0 years) and 16 demographically and cognitively matched adults who denied a history of FE (Mean age = 65.1, 37.5% female, Mean education = 15.1 years). Measures of whole-brain resting-state functional connectivity in the hippocampus, insula, and medial frontal cortex were derived for each group. Compared to the non-FE group, FE was associated with greater functional connectivity between the right hippocampus and bilateral temporal regions, and less functional connectivity between the right hippocampus and the right cerebellum and bilateral lingual gyri. The FE group showed less connectivity between the right and left insula and cingulate cortex, and between the right insula and regions of the left lateral temporal gyrus and dorsolateral prefrontal cortex. Finally, the FE group showed greater functional connectivity between the medial frontal cortex and the right lateral temporal gyrus and orbitofrontal cortex, and less functional connectivity with the right pre- and postcentral gyri. Results suggest that perceived FE in old age is associated with whole-brain functional connectivity differences involving the hippocampus, insula, and medial frontal cortex, consistent with models implicating age-associated changes in decision making and social cognition in FE.


Frailty and Perceived Financial Exploitation: Findings from the Finance, Cognition, and Health in Elders Study

Objective: Many older adults who are cognitively intact experience financial exploitation (FE), and the reasons for this are poorly understood. 

Methods: Data were gathered from 37 older adults (M age = 69.51, M education = 15.89, 62% female) from the Finance, Cognition, and Health in Elders Study (FINCHES). Twenty-four older adults who self-reported FE were demographically-matched according to age, education, race, and MoCA performance to thirteen older adults who denied experiencing FE. Participants completed the Tilburg Frailty Inventory. 

Results: FE participants reported greater total frailty (t = 2.06, p = .04) when compared to non-FE participants. Post-hoc analyses revealed that FE participants endorsed greater physical frailty (U = 89, p = .03), specifically poorer sensory functioning (hearing and vision). 

Discussion: Findings suggest frailty is associated with FE in old age and may represent a target for intervention programs for the financial wellbeing of older adults.

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