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Ranibizumab and aflibercept, two drugs used to treat retinal diseases, are excreted in the breast milk of nursing mothers who take the medications. The drugs contain an agent called anti-vascular endothelial growth factor (anti-VEGF), which blocks the development of a protein which stimulates the development of blood vessels. The protein, VEGF, is present in breast milk and plays a role in the development of the digestive system in infants.
A new study reports researchers have identified a signaling pathway that appears to be vital in angiogenesis. The findings could help in the development of treatments to improve blood flow in ischemic tissue.
A new study could help explain why children born to mothers infected by Zika are more likely to have microcephaly.
More research is needed on the link between maternal cannabis use and the health of newborns, researchers report.
According to researchers, targeting multiple angiogenesis pathways simultaneously could help overcome the resistance to anti-angiogenic treatment developed by glioblastoma brain cancer.