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University of Sheffield

·November 7, 2025·9 min read

New Therapy Reshapes Images That Fuel Psychosis

A new imagery-focused therapy called iMAPS may help people with psychosis gain control over disturbing mental images that fuel paranoia, fear, and hallucinations. In a feasibility trial of 45 participants, the approach showed strong patient engagement and meaningful reductions in distress by teaching individuals to understand, transform, and re-script intrusive images.

Featured Neurology Neuroscience

·July 1, 2023·5 min read

Artificial Intelligence is Transforming Early Detection of Dementia

Researchers developed CognoSpeak, an innovative AI tool that aims to streamline the diagnosis of dementia and Alzheimer’s. Utilizing virtual agents to engage patients in cognitive tests and analyzing their language and speech patterns, the tool provides a quick and efficient assessment.

Featured Neurology Neuroscience

·April 11, 2023·4 min read

Modified Botox Found to Give Long-Term Pain Relief After Nerve Injury Without Side Effects

A newly created elongated botulinum neurotoxin can alleviate symptoms of chronic pain without causing addiction or nerve damage leading to paralysis.

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Featured Neurology Neuroscience Open Neuroscience Articles

·January 13, 2022·3 min read

Heart Disease Causes Early Brain Dysfunction and Can Treble Key Alzheimer’s Protein

Heart disease that causes brain dysfunction can lead to the development of Alzheimer's disease and triples the amount of amyloid-beta in the brain.

Brain Cancer Featured Genetics Neurology Open Neuroscience Articles

·September 16, 2021·2 min read

New Gene Therapy Pathway Could Protect Us From Cancer and Dementia

A newly identified gene therapy pathway has the potential to protect us against dementia and cancer, researchers report.

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Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·June 12, 2021·6 min read

Frequent Strenuous Exercise Increases the Risk of Developing ALS in Certain People

Researchers have identified a causal link between strenuous exercise and ALS in people with genetic risk factors for the neurodegenerative disease. The study reports intense physical exercise contributes to motor neuron injury in those susceptible to ALS.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·March 23, 2021·4 min read

Parkinson’s Gene May Impair How New Neurons Are Made Throughout Our Lifetime

PINK1, a gene associated with Parkinson's disease, is not just responsible for the premature death of dopaminergic neurons, it also plays a key role in the neurogenesis of dopamine neurons throughout life.

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Featured Neurology Open Neuroscience Articles

·January 31, 2021·4 min read

Obesity May Exacerbate the Effects of Alzheimer’s Disease

Neuroimaging study reveals obesity may contribute towards neural tissue vulnerability in Alzheimer’s disease. Researchers say maintaining a healthy weight could help preserve brain structure for those in the early stages of Alzheimer’s.

Featured Neuroscience Open Neuroscience Articles Psychology

·March 31, 2020·4 min read

Depression and anxiety spiked immediately after COVID-19 lockdown announcement

The day following the lockdown of the UK amid the COVID-19 outbreak, 38% of study participants reported significant symptoms of depression, and 36% reported increased levels of anxiety. The day before lockdown, 16% reported depression, and 17% reported feelings of anxiety. The rates of depression and anxiety remained high for a week after the announcement, but not as high as was reported immediately following the lockdown.

Featured Genetics Neuroscience

·March 13, 2020·2 min read

Whole genomes of coronavirus from UK patients sequenced

Researchers have sequenced their first two genomes of COVID-19 from samples of patients in the UK. The genomes have been published on an international viral sequence database. The sequences will provide critical information to track the spread and evolution of the virus in the UK and worldwide.

Featured Neurology Neuroscience Psychology

·March 1, 2020·4 min read

Celiac disease can damage the brain

Celiac disease, an autoimmune response to ingesting gluten, has been linked to an increased risk of neurological damage and negative mental health outcomes. Those with celiac disease are more likely to experience depression, anxiety, and thoughts of self-harm, in addition to a reduction in reaction times and cognitive function. Neuroimaging of patients with the disorder reveals white matter changes in the brain.

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Featured Neuroscience Psychology

·February 7, 2020·2 min read

Brain training does not improve early number skills

Brain training exercises do not help boost early math learning. However, core thinking skills, including memory and attention, are key skills that support early math learning.

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