Autism-related genetic mutations occur in aging brains of Alzheimer’s patients
Genomic autism-related ADNP mutations were found in postmortem olfactory bulbs and hippocampi of Alzheimer's patients.... Read More...
Tau
Study shows extra virgin olive oil staves off multiple forms of dementia in mice
Extra virgin olive oil may protect against cognitive declines linked to tauopathy diseases, specifically frontotemporal dementia.... Read More...
Inflammatory processes drive progression of Alzheimer’s and other brain diseases
The NLPR3 inflammasome and the inflammatory response it triggers play a critical role in the emergence of tau pathology. ... Read More...
How Alzheimer’s disease spreads through the brain
Tau buildup associated with Alzheimer's disease is not, in itself, harmful, but the cellular process it disrupts kills neurons.... Read More...
Exercise could slow withering effects of Alzheimer’s
For those with mild cognitive impairment (MCI) and other risk factors for Alzheimer's disease, participating in aerobic exercise several times a week may slow neurodegeneration. Aerobic exercise reduced hippocampal atrophy in those with MCI. ... Read More...
How the eyes might be windows to the risk of Alzheimer’s disease
Adults with mild cognitive impairment (MCI), a precursor to Alzheimer's disease, have greater pupil dilation when taking cognitive tests than their cognitively normal peers. Task-evoked pupillary response may be a cost-effective, and low invasive screening test for those at genetic risk for Alzheimer's before the symptoms of the disease take hold. ... Read More...
Alzheimer’s disease destroys neurons that keep us awake
Tau accumulations disrupt wake-promoting neurons. The findings help explain why day-time napping and sleep disruptions are often reported in Alzheimer's patients.... Read More...
Routine hits playing football cause damage to the brain
Sustained hits following one season of playing football are enough to cause structural alterations to the brain. When players sustain a concussion, structural brain integrity decreases, and levels of tau increase. Researchers say, while concussions are a prime concern for those who play football, sustained hits also pose a threat to neurological health.... Read More...
Super-resolution microscopy sheds light on how dementia protein becomes dysfunctional
A microscopy study revealed tau controls Fyn clustering in dendrites. The findings shed new light on how certain forms of dementia may occur.... Read More...
Novel discovery of links between liver dysfunction and Alzheimer’s disease
A link between liver dysfunction and Alzheimer's disease has been discovered. The findings add to the understanding of the role metabolic dysfunction plays in the neurodegenerative disease.... Read More...
Risk and progression of Alzheimer’s disease differ by gender
The risk of developing Alzheimer's disease is increased, and progression more rapid in women due to larger brain-wide accumulation and acceleration in the spread of tau. ... Read More...
Sorting protein in neurons defends against neurodegenerative disease
VPS35 is a novel critical component of tau metabolism and the pathology of neurodegenerative diseases. ... Read More...