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Tau

Featured Genetics Neurology Neuroscience

·August 6, 2026·12 min read

Tau Infiltrates Mitochondria to Drive Alzheimer’s

Hyperphosphorylated tau invades mitochondria and triggers reverse electron transport, opening a novel target for treating Alzheimer's disease and tauopathies.

Featured Neurology Neuroscience Psychology

·August 4, 2026·8 min read

Brain PET Scans Link Late-Onset Psychosis to Tau and Amyloid

A new study using PET imaging reveals that 65% of patients with late-onset psychosis exhibit tau protein buildup in the brain, linking midlife hallucinations and delusions to underlying neurodegeneration.

Featured Neurology Neuroscience

·July 17, 2026·12 min read

Tau Buildup in PSP Affects Distant Thinking Brain Networks

Cognitive and behavioral symptoms in Progressive Supranuclear Palsy (PSP) are driven by the remote circuit disruption of a shared frontoparietal architecture called the "PSP-tau network."

Featured Neurology Neuroscience

·July 8, 2026·11 min read

Alcohol Alters Brain Flexibility Based on Hidden Dementia Markings

Alcohol interacts differently with amyloid-beta and tau pathologies in the brain's corticostriatal circuit.

Featured Genetics Neurology Neuroscience

·June 29, 2026·12 min read

Arc Protein Found to Spread Toxic Tau in Alzheimer’s

The native brain protein Arc mediates the intercellular transmission of toxic Tau via extracellular vesicles in Alzheimer's disease. While Arc helps sick neurons survive longer by expelling toxic Tau aggregates, it simultaneously promotes the spread of pathology to healthy cells, identifying the extracellular space as a prime "mid-flight" therapeutic target.

Featured Neurology Neuroscience

·May 15, 2026·7 min read

Rogue Antibodies Drive Tau Pathology

A new study establishes a direct causal link between IgLON5 antibodies and Tau pathology. By applying patient antibodies to mouse models, the team discovered that antibody-induced clustering of cell-surface IgLON5 proteins sparks profound neuronal hyperactivity.

This shows a connectome view of a human brain.

Featured Neurology Neuroscience

·April 8, 2026·10 min read

Brain’s Unique Wiring Determines How Alzheimer’s Spreads

A 10-year study proves that Alzheimer’s tau tangles spread via an individual's unique neural connections. The findings confirm that targeting tau as it travels between synapses could halt the disease's progression.

This shows the vascular system in the head and neck.

Featured Neurology Neuroscience

·February 27, 2026·7 min read

Minimally Invasive Surgery Could Treat Alzheimer’s

Scientists are testing a plastic surgery technique to bypass blocked lymphatic pathways and flush Alzheimer's-linked toxins out of the body.

Featured Neurology Neuroscience

·July 22, 2025·6 min read

Synaptic Tau and Astrocytes Drive PSP Progression

ew research uncovers how tau pathology spreads and damages synapses in progressive supranuclear palsy (PSP). Using human postmortem tissue and live brain slice models, scientists showed tau accumulates in both pre- and postsynaptic terminals, likely propagating neuron-to-neuron.

Featured Genetics Neurology Neuroscience

·July 9, 2025·7 min read

Genes and Brain Wiring Team Up in Alzheimer’s Spread

A new study reveals how genes influence where and how Alzheimer’s-related tau protein spreads in the brain. By combining imaging, gene data, and advanced modeling, researchers uncovered four gene pathways that either amplify or resist tau buildup, depending on brain connectivity.

Featured Neurology Neuroscience

·May 30, 2025·4 min read

SSRIs Restore Brain Function in Alzheimer’s

A new study suggests that SSRIs, commonly prescribed antidepressants, may reduce biological markers of Alzheimer’s disease. In a cohort of 191 individuals, AD patients on SSRIs had lower levels of plasma phosphorylated tau-181, a key indicator of disease severity.

Featured Neurology Neuroscience

·May 29, 2025·6 min read

Sleep Aid May Protect Brain from Alzheimer’s Damage

A common sleep medication, lemborexant, may do more than promote rest—it appears to reduce harmful tau buildup and protect the brain from neurodegeneration in mouse models of Alzheimer’s disease. Researchers found that this orexin receptor antagonist not only restored healthier sleep patterns but also preserved brain structure and reduced inflammation.

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Tau

Tau Infiltrates Mitochondria to Drive Alzheimer’s

Brain PET Scans Link Late-Onset Psychosis to Tau and Amyloid

Tau Buildup in PSP Affects Distant Thinking Brain Networks

Alcohol Alters Brain Flexibility Based on Hidden Dementia Markings

Arc Protein Found to Spread Toxic Tau in Alzheimer’s

Rogue Antibodies Drive Tau Pathology

Brain’s Unique Wiring Determines How Alzheimer’s Spreads

Minimally Invasive Surgery Could Treat Alzheimer’s

Synaptic Tau and Astrocytes Drive PSP Progression

Genes and Brain Wiring Team Up in Alzheimer’s Spread

SSRIs Restore Brain Function in Alzheimer’s

Sleep Aid May Protect Brain from Alzheimer’s Damage

Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

Youth Protein TIMP2 Restores Immune Function in the Aging Brain

Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

Study of Brain Immune Cells Reveals New Clues to Alzheimer’s Disease Progression

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