Alzheimer’s risk genes converge on microglia
Findings indicate a large part of the genetic risk of Alzheimer's involves a microglial response to amyloid-beta.... Read More...
Tau
Could targeting an Alzheimer’s-associated protein prevent Autism?
Reducing levels of the Alzheimer's related Tau protein prevents autism-like behaviors in mouse models. Tau reduction also prevented seizures in the animals.... Read More...
Beta-arrestin-2 increases neurotoxic tau driving frontotemporal dementia
The protein beta-arrestin-2 increases tau tangle accumulation in Alzheimer's disease and frontotemporal dementia but interfering with the removal of excess tau from the brain.... Read More...
Subtle decline in cognition predicts progression to Alzheimer’s pathology
Cognitive performance may predict the progression from normal to abnormal levels of Alzheimer's associated amyloid-beta.... Read More...
Unexpected connection between gliomas and neurodegenerative diseases
Study finds significant expression of the Alzheimer's related Tau protein in glioma cells, especially in patients with better prognoses.... Read More...
Losing a night of sleep may increase blood levels of Alzheimer’s biomarker
Following a night of sleep deprivations, levels of tau in the blood increase 17% in healthy young men.... Read More...
Autism-related genetic mutations occur in aging brains of Alzheimer’s patients
Genomic autism-related ADNP mutations were found in postmortem olfactory bulbs and hippocampi of Alzheimer's patients.... Read More...
Study shows extra virgin olive oil staves off multiple forms of dementia in mice
Extra virgin olive oil may protect against cognitive declines linked to tauopathy diseases, specifically frontotemporal dementia.... Read More...
Inflammatory processes drive progression of Alzheimer’s and other brain diseases
The NLPR3 inflammasome and the inflammatory response it triggers play a critical role in the emergence of tau pathology. ... Read More...
How Alzheimer’s disease spreads through the brain
Tau buildup associated with Alzheimer's disease is not, in itself, harmful, but the cellular process it disrupts kills neurons.... Read More...
Exercise could slow withering effects of Alzheimer’s
For those with mild cognitive impairment (MCI) and other risk factors for Alzheimer's disease, participating in aerobic exercise several times a week may slow neurodegeneration. Aerobic exercise reduced hippocampal atrophy in those with MCI. ... Read More...
How the eyes might be windows to the risk of Alzheimer’s disease
Adults with mild cognitive impairment (MCI), a precursor to Alzheimer's disease, have greater pupil dilation when taking cognitive tests than their cognitively normal peers. Task-evoked pupillary response may be a cost-effective, and low invasive screening test for those at genetic risk for Alzheimer's before the symptoms of the disease take hold. ... Read More...