SuperAgers who maintain their cognitive abilities have resistance to the development of Alzheimer's related tau tangles. The resistance to tangles may help to preserve memory. Read More
Study identifies a new "seeding" process in neurons that could be a cause of dementia and Alzheimer's disease. Read More
A new automated method can identify and track the development of tau deposits in the brain. The method could lead to an earlier diagnosis of Alzheimer's disease. Read More
Impaired blood flow to specific areas of the brain coincides with Tau buildup in Alzheimer's patients. As cognition declines, the relationship between vascular dysfunction and Tau accumulation strengthens. Read More
Altered expression of FYN, a gene associated with the production of Tau, was identified in the brains of people addicted to heroin. Findings suggest opioid use can affect the brain in a way that might cause vulnerability in neural systems that can trigger neurodegeneration later in life. Read More
Early postmenopausal estrogen replacement therapy may protect some women from developing Alzheimer's disease. Read More
Blood samples taken from people enrolled in an Alzheimer's research study revealed higher levels of phosphorylated tau 217 that correlated with the presence of amyloid plaques. People with amyloid in their brains had up to three times more of the tau protein in their blood than those who had no evidence of amyloid accumulation. The higher levels of the protein were evident even in people with no signs of cognitive decline. Read More
Children suffering from a form of autism called ADNP syndrome may benefit from an experimental drug designed to treat Alzheimer's disease. Read More
PET neuroimaging reveals super-agers and those whose cognitive skills are above the norm for an advanced age have an increased resistance to tau and amyloid proteins. Read More
Tau spreads through the human brain via neural communication pathways. The spread is accelerated by the presence of amyloid-beta. Read More
Findings indicate a large part of the genetic risk of Alzheimer's involves a microglial response to amyloid-beta. Read More
Reducing levels of the Alzheimer's related Tau protein prevents autism-like behaviors in mouse models. Tau reduction also prevented seizures in the animals. Read More
