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How chronic stress changes the brain, and what you can do to reverse the damage

Chronic stress can affect a person's health and mental well being. Due to the COVID-19 virus, chronic stress is on the rise worldwide. Researchers examine the general and psychological health implications of chronic stress and suggest some methods we can adopt to keep our stress levels in check. Read More

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Antidepressant harms baby neurons in lab-grown ‘mini-brains’

Using a mini-brain model, researchers report the popular SSRI antidepressant Paroxetine can induce brain cell developmental abnormalities that could lead to adverse effects in children. Read More

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Extended antidepressant use creates physical dependence

Long-term use of antidepressants can create physical dependence and severe withdrawal symptoms for patients looking to stop their treatment. Patients who quit their medication often experience Antidepressant Discontinuation Syndrome, which results in flu-like symptoms, insomnia, nausea, and other symptoms associated with withdrawal. Read More

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Neural signature identifies people likely to respond to antidepressant medication

A new machine-learning algorithm that analyzes EEG data can identify reliable and robust neural signatures associated with antidepressant treatment response. Read More

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Are some antidepressants less risky for pregnant women?

Alteration of placental serotonin levels due to maternal depression or antidepressant use may be associated with the disruption of placental estrogen production. Read More

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The effect of taking antidepressants during pregnancy

Exposure to antidepressants during the first few weeks of pregnancy has long term implications for sensory processing in the offspring. Read More

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Turning to turkey’s tryptophan to boost mood? Not so fast

Research examines the myths and science behind how the amino acid tryptophan, associated with turkey, affects mood. Read More

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AI helps scientists predict depression outcomes

Artificial intelligence technology was able to identify specific brain regions which were most important for predicting whether a person with depression would respond to SSRI antidepressants. Read More

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Common antidepressant may not reduce depression symptoms, but does reduce anxiety

Sertraline (Zoloft), a commonly prescribed SSRI antidepressant, may not be as effective at treating depression within 6 weeks as previously thought. However, the drug is effective for treating anxiety symptoms. Read More

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How serotonin and a popular anti-depressant affect the gut’s microbiota

Serotonin and SSRIs like Prozac can have a major effect on gut bacteria. When exposed to serotonin, specific gut bacteria grew to higher levels. However, when exposed to SSRIs, the bacterium grew to much lower levels in mouse models. Read More

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Psychedelic drugs: would you accept a prescription? It depends if you’ve tried them before

Numerous studies have linked controlled psychedelics to improvements in mental health conditions such as depression and PTSD. In March, the FDA approved Esketamine as a treatment for depression. However, with much stigma surrounding psychedelics, researchers question how many patients would take psychedelic medications if prescribed to them. According to a new study, 40% of people with no experience of psychedelics would be unlikely to take the prescription due to fears of 'brain damage' or a 'bad trip'. Read More

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How a popular antidepressant drug could rewire the brain

Fluoxetine rearranges nerve fibers in the hippocampus of mice, a new study reports. Read More

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