Latest

SSRIs

·July 6, 2026·12 min read

Biomarkers Boost Antidepressant Success Rates by 67%

A new study demonstrates that combining fMRI brain connectivity, cognitive reward testing, and clinical markers to guide antidepressant selection increases patient response rates by nearly 67%.

Featured Neuroscience Psychology

·June 8, 2026·8 min read

SSRIs Push Serotonin Neurons in Opposite Directions

A new study maps the distinct gene-expression changes induced by fluoxetine inside the brain's primary serotonin hub, the Dorsal Raphe Nucleus.

Auditory Neuroscience Featured Neuroscience Psychology

·April 20, 2026·7 min read

SSRIs May Trigger Tinnitus

A new study identifies a specific serotonin circuit that triggers the auditory system, explaining why SSRIs can worsen tinnitus and offering a new target for treatment.

Autism Featured Neuroscience

·April 20, 2026·8 min read

Study Links Sterol-Inhibiting Drugs to Autism Risk

Astudy of 6 million births links common medications that inhibit cholesterol synthesis, including certain antidepressants and beta-blockers—to a 1.47-fold increased risk of autism.

This shows a scale, a pill and mushrooms.

Featured Neuroscience Psychology

·March 18, 2026·9 min read

Psychedelics Match, But Don’t Beat, Traditional Antidepressants

New research reveals that the perceived advantage of psychedelics over antidepressants disappears when the "knowledge of treatment" factor is equalized.

Featured Neuroscience Psychology

·February 13, 2026·8 min read

Antidepressants May Safeguard Against Preterm Birth Risks

Does treating depression with antidepressants during pregnancy harm the baby? A massive new study reveals that while SSRIs increase gestational diabetes risk, they also protect against preterm birth.

Featured Neuroscience Psychology

·October 30, 2025·6 min read

Common Antidepressant Eases Core Symptoms Within Two Weeks

A new analysis of the PANDA clinical trial reveals that sertraline, one of the most prescribed antidepressants, improves key emotional symptoms of depression—such as sadness, self-loathing, and suicidal thoughts—within just two weeks of treatment. Using network analysis to assess individual symptoms, researchers found that the drug also eased anxiety early on, while somatic effects like fatigue and low libido appeared but later stabilized.

This shows a woman, hearts, a brain, and brain waves.

Featured Neuroscience Psychology

·October 13, 2025·6 min read

EEG Test May Reveal Who Loses Libido on Antidepressants

A new study reveals that serotonin levels in the brain, measured using a simple EEG-based test, can predict who will experience sexual side effects from SSRI antidepressants. Researchers found that people with higher serotonin activity before treatment were significantly more likely to have difficulty reaching orgasm during antidepressant use.

Featured Genetics Neuroscience Psychology

·July 19, 2025·7 min read

Why Antidepressants Work Better for Some

A meta-analysis of gene expression data from humans and rodents reveals key biological pathways influencing response to the antidepressant fluoxetine. The study highlights the role of immune-related pathways, including toll-like receptor signaling, and neural signal transduction mechanisms in distinguishing responders from non-responders.

Featured Neuroscience Psychology

·July 7, 2025·5 min read

Timing of Prozac Treatment Shapes Lasting Mood, Brain Changes

New research reveals that the developmental timing of fluoxetine (Prozac) treatment profoundly influences long-term mood and brain function. In a rodent model, early postnatal treatment in males led to persistent anxiety and depression-like behaviors, while adolescent treatment reduced these behaviors.

Featured Neurology Neuroscience

·May 30, 2025·4 min read

SSRIs Restore Brain Function in Alzheimer’s

A new study suggests that SSRIs, commonly prescribed antidepressants, may reduce biological markers of Alzheimer’s disease. In a cohort of 191 individuals, AD patients on SSRIs had lower levels of plasma phosphorylated tau-181, a key indicator of disease severity.

Featured Neuroscience Psychology

·May 7, 2025·8 min read

SSRI Exposure in the Womb May Rewire Brain Circuits

New research suggests that prenatal exposure to SSRIs may alter brain development in ways that increase the risk of depression and anxiety later in life. Using mice and human data, scientists found that early-life SSRI exposure heightened activity in brain fear circuits, a pattern not observed in offspring of depressed mothers who did not take SSRIs.

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SSRIs

Biomarkers Boost Antidepressant Success Rates by 67%

SSRIs Push Serotonin Neurons in Opposite Directions

SSRIs May Trigger Tinnitus

Study Links Sterol-Inhibiting Drugs to Autism Risk

Psychedelics Match, But Don’t Beat, Traditional Antidepressants

Antidepressants May Safeguard Against Preterm Birth Risks

Common Antidepressant Eases Core Symptoms Within Two Weeks

EEG Test May Reveal Who Loses Libido on Antidepressants

Why Antidepressants Work Better for Some

Timing of Prozac Treatment Shapes Lasting Mood, Brain Changes

SSRIs Restore Brain Function in Alzheimer’s

SSRI Exposure in the Womb May Rewire Brain Circuits

How Severe Illness During Pregnancy Alters Fetal Brain Development

Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

Youth Protein TIMP2 Restores Immune Function in the Aging Brain

Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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