SSRI's, ketamine, and tricyclic antidepressants all bind with TrkB. The findings challenge the roles serotonin and glutamate receptors play in the effects of antidepressant medications. Read More
With the risk of potential for abuse, some new fast-acting antidepressants, like Ketamine, may not be a magic "cure-all" for depression. Read More
Activity of the c-Fos gene begins the increase on the ninth day of exposure to antidepressants. By day 14, mice showed behavioral changes associated with SSRI use. This may explain why suicide rates drop after nine days of treatment, and symptoms of depression improve after three weeks. Read More
The antipsychotic medication clozapine can trigger severe obsessive-compulsive symptoms (OCS) in patients. Adding aripiprazole can help manage clozapine-associated OCS. Read More
The SSRI sertraline (Zoloft), if taken while pregnant, can result in birth defects caused by the drug damaging a cell's genetic information. Researchers report one potential way to counter the effect is with specific antioxidants. Read More
Increased levels of serotonin transporters in the amygdala may explain why some people are more prone to anxiety than others. Read More
Children exposed to SSRI antidepressants in utero had an increased risk of experiencing language and cognitive deficits in kindergarten. Read More
Chronic stress can affect a person's health and mental well being. Due to the COVID-19 virus, chronic stress is on the rise worldwide. Researchers examine the general and psychological health implications of chronic stress and suggest some methods we can adopt to keep our stress levels in check. Read More
Using a mini-brain model, researchers report the popular SSRI antidepressant Paroxetine can induce brain cell developmental abnormalities that could lead to adverse effects in children. Read More
Long-term use of antidepressants can create physical dependence and severe withdrawal symptoms for patients looking to stop their treatment. Patients who quit their medication often experience Antidepressant Discontinuation Syndrome, which results in flu-like symptoms, insomnia, nausea, and other symptoms associated with withdrawal. Read More
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A new machine-learning algorithm that analyzes EEG data can identify reliable and robust neural signatures associated with antidepressant treatment response. Read More
Alteration of placental serotonin levels due to maternal depression or antidepressant use may be associated with the disruption of placental estrogen production. Read More
