Using EEG technology, researchers were able to detect pathological brain activity associated with seizures up to thirty minutes before a seizure occurred in patients with temporal lobe epilepsy. The ability to detect seizure activity early could allow for the modulation of affected brain regions as a therapeutic option.
A genetic subtype of ASD and schizophrenia have a duplicate gene that triggers overactivity in neural circuits, leading to social deficits and seizures. When researchers reduced the level of the PRRT2 gene in mouse models of 16p11.2 duplication syndrome, social behaviors were restored and seizure activity decreased.
Cannabidiol, or CBD, blocks the ability of lysophosphatidylinositol (LPI) to amplify neural signals in the hippocampus. LPI weakens the signals that counter seizures, further explaining the value of CBD to treat epilepsy.
Researchers have identified a correlation between control energy consumption and glucose metabolism in temporal lobe epilepsy. The mechanism provides a biological basis for the application of network control theory in the study of brain dynamics.
People who contracted COVID-19 are significantly more likely to develop epilepsy or experience a seizure within 6 months of infection than those who contracted influenza.
2-3% of patients with Monkeypox experience seizures and encephalitis, a new study reports. Researchers say almost half of people with Monkeypox infection also report mental health problems, including depression and anxiety, and other neurological symptoms like headaches as a result of the infection.
Seizures originate from an excess of excitatory over inhibitory neural activity in confined regions of the brain, and spread only when they overcome strong inhibitory activity in surrounding regions.
When dysfunctional, somatostatin interneurons drive brain activity and provoke seizures.
Scientists have identified three acidic cannabinoids in cannabis that reduces seizure activity in mouse models of Dravet syndrome.
The release of 2-AG, a natural endocannabinoid that is suggested to be the brain's equivalent to THC, dampens down seizure activity but increases post-seizure oxygen deprivation in the brain.
A new system translates EEG data into a 3D movie which shows activity in all recorded regions of the brain. The heat map shows where seizures start and spread throughout the patient's brain, in addition to evaluating the speed of activity during a seizure.
Alterations in the local network of specific brain regions can predict the progression of epilepsy, and determine whether surgery is a viable option for the patient.